Gideon Koren

TL;DR: The elimination of 1 repolarizing current was associated with downregulation of the reciprocal repolarization current rather than with the compensatory upregulation observed previously in LQTS mouse models, which suggests that mutant KvLQT1 and HERG interacted with the reciprocal wild-type alpha subunits of rabbit ERG and Kv LQT 1, respectively.

TL;DR: None demonstrated a significant benefit of EMLA for any of the outcome measures used to assess pain (ie, behavioral pain scores, infant crying, heart rate, blood pressure, respiratory rate, oxygenation parameters).

TL;DR: A significant gap is identified between the accumulating knowledge of PK changes in pregnant women and the authors' understanding of their clinical impact for both mother and fetus, and it is essential for clinicians to be aware of these unique pregnancy-related changes in PK, and to critically examine their clinical implications.

TL;DR: A simple and clinically relevant method for evaluation of the severity of nausea and vomiting of pregnancy that can be used for both clinical practice and research is established and Clinicians and researchers can easily use PUQE.

TL;DR: This study aims to determine whether this drug increases the baseline rate of major malformations in women treated with Zofran for nausea and vomiting during pregnancy.