G
Giuliano Binetti
Researcher at Sacred Heart Hospital
Publications - 250
Citations - 13455
Giuliano Binetti is an academic researcher from Sacred Heart Hospital. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 60, co-authored 234 publications receiving 11295 citations. Previous affiliations of Giuliano Binetti include Massachusetts Institute of Technology.
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A novel deletion in progranulin gene is associated with FTDP-17 and CBS.
Luisa Benussi,Giuliano Binetti,Elena Sina,Lara Gigola,Thomas Bettecken,Thomas Meitinger,Roberta Ghidoni +6 more
TL;DR: An extensive clinical and genetic characterization of two Italian pedigrees presenting with FFTD is provided, identifying a novel 4 bp deletion mutation in exon 7 of PGRN gene associated with a variable clinical presentation ranging from FTDP-17 to corticobasal syndrome.
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Behavioral disorders in Alzheimer disease: a transcultural perspective
Giuliano Binetti,Michael S. Mega,Eugenio Magni,Alessandro Padovani,Luca Rozzini,Angelo Bianchetti,Marco Trabucchi,Jeffrey L. Cummings +7 more
TL;DR: The results indicate that NPI is a reliable instrument with which to study transcultural differences in the presentation of neuropsychiatric disturbances in patients with AD, and suggests a biological origin of the disorders.
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Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease
Aurelia Santoro,Valentina Balbi,Elisa Balducci,Chiara Pirazzini,Francesca Rosini,Francesca Tavano,Alessandro Achilli,Alessandro Achilli,Paola Siviero,Nadia Minicuci,Elena Bellavista,Michele Mishto,Michele Mishto,Stefano Salvioli,Francesca Marchegiani,Maurizio Cardelli,Fabiola Olivieri,Benedetta Nacmias,Andrea Maria Chiamenti,Luisa Benussi,Roberta Ghidoni,Giuseppina Rose,Carlo Gabelli,Giuliano Binetti,Sandro Sorbi,Gaetano Crepaldi,Giuseppe Passarino,Antonio Torroni,Claudio Franceschi +28 more
TL;DR: The results indicate that high resolution analysis of inherited mtDNA sequence variation can help in identifying both ancient polymorphisms defining sub-haplogroups and the accumulation of sporadic mutations associated with complex traits such as AD.
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Coma in a patient with Alzheimer's disease taking low dose trazodone and gingko biloba.
TL;DR: A patient with Alzheimer's disease who developed coma a few days after starting low dose trazodone associated with ginkgo biloba was reversed by flumazenil, a specific antagonist of the benzodiazepine (BDZ) receptor.
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Cytosol protein kinase C downregulation in fibroblasts from Alzheimer's disease patients
Stefano Govoni,S. Bergamaschi,Marco Racchi,Fiorenzo Battaini,Giuliano Binetti,Angelo Bianchetti,M. Trabucchi +6 more
TL;DR: The data suggest that the changes in PKC phosphorylating activity represent a diffuse cellular defect in AD and are not confined to the brain.