G
Giuliano Binetti
Researcher at Sacred Heart Hospital
Publications - 250
Citations - 13455
Giuliano Binetti is an academic researcher from Sacred Heart Hospital. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 60, co-authored 234 publications receiving 11295 citations. Previous affiliations of Giuliano Binetti include Massachusetts Institute of Technology.
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Journal ArticleDOI
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Itziar de Rojas,Itziar de Rojas,Sonia Moreno-Grau,Sonia Moreno-Grau,Niccolò Tesi,Benjamin Grenier-Boley,Victor Andrade,Victor Andrade,Iris E. Jansen,Nancy L. Pedersen,Najada Stringa,Anna Zettergren,Isabel Hernández,Isabel Hernández,Laura Montrreal,Carmen Antúnez,Anna Antonell,Rick M. Tankard,Joshua C. Bis,Rebecca Sims,Céline Bellenguez,Inés Quintela,Antonio González-Pérez,Miguel Calero,Emilio Franco-Macías,Juan Macías,Rafael Blesa,Rafael Blesa,Laura Cervera-Carles,Laura Cervera-Carles,Manuel Menéndez-González,Manuel Menéndez-González,Ana Frank-García,Jose Luis Royo,Fermin Moreno,Raquel Huerto Vilas,Miquel Baquero,Monica Diez-Fairen,Carmen Lage,Carmen Lage,Sebastian Garcia-Madrona,Pablo Garcia-Gonzalez,Emilio Alarcón-Martín,Emilio Alarcón-Martín,Sergi Valero,Sergi Valero,Oscar Sotolongo-Grau,Abbe Ullgren,Abbe Ullgren,Adam C. Naj,Afina W. Lemstra,Alba Benaque,Alba Pérez-Cordón,Alberto Benussi,Alberto Rábano,Alessandro Padovani,Alessio Squassina,Alexandre de Mendonça,Alfonso Arias Pastor,Almar A.L. Kok,Alun Meggy,Ana Belen Pastor,Ana Espinosa,Ana Espinosa,Anaïs Corma-Gómez,Angel Martin Montes,Angel Martin Montes,Angela Sanabria,Angela Sanabria,Anita L. DeStefano,Anja Schneider,Anja Schneider,Annakaisa Haapasalo,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Anne Tybjærg-Hansen,Annette M. Hartmann,Annika Spottke,Annika Spottke,Arturo Corbatón-Anchuelo,Arvid Rongve,Barbara Borroni,Beatrice Arosio,Benedetta Nacmias,Børge G. Nordestgaard,Børge G. Nordestgaard,Brian W. Kunkle,Camille Charbonnier,Carla Abdelnour,Carla Abdelnour,Carlo Masullo,Carmen Martinez Rodriguez,Carmen Munoz-Fernandez,Carole Dufouil,Caroline Graff,Caroline Graff,C. Ferreira,C. Chillotti,Chandra A. Reynolds,Chiara Fenoglio,Christine Van Broeckhoven,Christopher M. Clark,Claudia Pisanu,Claudia L. Satizabal,Claudia L. Satizabal,Clive Holmes,Dolores Buiza-Rueda,Dolores Buiza-Rueda,Dag Aarsland,Dag Aarsland,Dan Rujescu,Daniel Alcolea,Daniel Alcolea,Daniela Galimberti,David Wallon,Davide Seripa,Edna Grünblatt,Efthimios Dardiotis,Emrah Düzel,Emrah Düzel,Elio Scarpini,Elisa Conti,Elisa Rubino,Ellen Gelpi,Eloy Rodríguez-Rodríguez,Eloy Rodríguez-Rodríguez,Emmanuelle Duron,Emmanuelle Duron,Eric Boerwinkle,Eric Boerwinkle,Evelyn Ferri,Fabrizio Tagliavini,Fahri Küçükali,Florence Pasquier,Florentino Sanchez-Garcia,Francesca Mangialasche,Frank Jessen,Frank Jessen,Gaël Nicolas,Geir Selbæk,Geir Selbæk,Gemma Ortega,Gemma Ortega,Geneviève Chêne,Georgios M. Hadjigeorgiou,Giacomina Rossi,Gianfranco Spalletta,Giorgio Giaccone,Giulia Grande,Giuliano Binetti,Goran Papenberg,Harald Hampel,Henri Bailly,Henrik Zetterberg,Hilkka Soininen,Ida K. Karlsson,Ida K. Karlsson,Ignacio Alvarez,Ildebrando Appollonio,Ina Giegling,Ingmar Skoog,Ingvild Saltvedt,Innocenzo Rainero,Irene Rosas Allende,Jakub Hort,Janine Diehl-Schmid,Jasper Van Dongen,Jean-Sébastien Vidal,Jenni Lehtisalo,Jenni Lehtisalo,Jens Wiltfang,Jens Wiltfang,Jens Wiltfang,Jesper Qvist Thomassen,Johannes Kornhuber,Jonathan L. Haines,Jonathan Vogelgsang,Jonathan Vogelgsang,Juan A. Pineda,Juan Fortea,Juan Fortea,Julius Popp,Julius Popp,Jürgen Deckert,Katharina Buerger,Katharina Buerger,Kevin Morgan,Klaus Fließbach,Kristel Sleegers,Laura Molina-Porcel,Lena Kilander,Leonie Weinhold,Lindsay A. Farrer,Li-San Wang,Luca Kleineidam,Luca Kleineidam,Lucia Farotti,Lucilla Parnetti,Lucio Tremolizzo,Lucrezia Hausner,Luisa Benussi,Lutz Froelich,M. Arfan Ikram,M. Candida Deniz-Naranjo,Magda Tsolaki,Maitée Rosende-Roca,Maitée Rosende-Roca,Malin Löwenmark,Marc Hulsman,Marco Spallazzi,Margaret A. Pericak-Vance,Margaret M. Esiri,Maria Bernal Sanchez-Arjona,Maria Carolina Dalmasso,María Teresa Martínez-Larrad,Marina Arcaro,Markus M. Nöthen,Marta Fernandez-Fuertes,Martin Dichgans,Martin Dichgans,Martin Ingelsson,Martin J. Herrmann,Martin Scherer,Martin Vyhnalek,Mary H. Kosmidis,Mary Yannakoulia,Matthias Schmid,Matthias Schmid,Michael Ewers,Michael Ewers,Michael T. Heneka,Michael T. Heneka,Michael Wagner,Michael Wagner,Michela Scamosci,Miia Kivipelto,Mikko Hiltunen,Miren Zulaica,Montserrat Alegret,Montserrat Alegret,Myriam Fornage,Natalia Roberto,Natasja M. van Schoor,Nazib M Seidu,Nerisa Banaj,Nicola J. Armstrong,Nikolaos Scarmeas,Nikolaos Scarmeas,Norbert Scherbaum,Oliver Goldhardt,Oliver Hanon,Oliver Peters,Oliver Peters,Olivia Anna Skrobot,Olivier Quenez,Ondrej Lerch,Paola Bossù,Paolo Caffarra,Paolo Rossi,Paraskevi Sakka,Per Hoffmann,Per Hoffmann,Peter Holmans,Peter Fischer,Peter Riederer,Qiong Yang,Rachel Marshall,Rajesh N. Kalaria,Richard Mayeux,Rik Vandenberghe,Roberta Cecchetti,Roberta Ghidoni,Ruth Frikke-Schmidt,Sandro Sorbi,Sara Hägg,Sebastiaan Engelborghs,Seppo Helisalmi,Sigrid Botne Sando,Silke Kern,Silvana Archetti,Silvia Boschi,Silvia Fostinelli,Silvia Gil,Silvia Mendoza,Simon Mead,Simona Ciccone,Srdjan Djurovic,Srdjan Djurovic,Stefanie Heilmann-Heimbach,Steffi G. Riedel-Heller,Teemu Kuulasmaa,Teodoro Del Ser,Thibaud Lebouvier,Thomas Polak,Tiia Ngandu,Tiia Ngandu,Timo Grimmer,Valentina Bessi,Valentina Escott-Price,Vilmantas Giedraitis,Vincent Deramecourt,Wolfgang Maier,Wolfgang Maier,Xueqiu Jian,Yolande A.L. Pijnenburg,Patrick Gavin Kehoe,Guillermo García-Ribas,Pascual Sánchez-Juan,Pascual Sánchez-Juan,Pau Pastor,Jordi Pérez-Tur,Jordi Pérez-Tur,Gerard Piñol-Ripoll,Adolfo López de Munain,Jose María García-Alberca,María J. Bullido,Victoria Alvarez,Alberto Lleó,Alberto Lleó,Luis Miguel Real,Pablo Mir,Pablo Mir,Miguel Medina,Philip Scheltens,Henne Holstege,Marta Marquié,Marta Marquié,María Eugenia Sáez,Angel Carracedo,Philippe Amouyel,Gerard D. Schellenberg,Julie Williams,Sudha Seshadri,Cornelia M. van Duijn,Cornelia M. van Duijn,Karen A. Mather,Karen A. Mather,Raquel Sánchez-Valle,Manuel Serrano-Ríos,Adelina Orellana,Adelina Orellana,Lluís Tárraga,Lluís Tárraga,Kaj Blennow,Kaj Blennow,Martijn Huisman,Martijn Huisman,Ole A. Andreassen,Ole A. Andreassen,Danielle Posthuma,Jordi Clarimón,Jordi Clarimón,Mercè Boada,Mercè Boada,Wiesje M. van der Flier,Alfredo Ramirez,Jean-Charles Lambert,Sven J. van der Lee,Agustín Ruiz,Agustín Ruiz +359 more
TL;DR: In this article, a large genetic association study was performed by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190).
Journal ArticleDOI
Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells
Laura Gasparini,Marco Racchi,Luisa Benussi,Daniela Curti,Giuliano Binetti,Angelo Bianchetti,Marco Trabucchi,Stefano Govoni +7 more
TL;DR: The results suggest that the inhibition of energy metabolism can influence APP processing leading to a decreased secretion of non-amyloidogenic fragments of APP.
Journal ArticleDOI
Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric Electroencephalogram study
Claudio Babiloni,Luisa Benussi,Giuliano Binetti,Emanuele Cassetta,Gloria Dal Forno,Claudio Del Percio,Florinda Ferreri,Raffaele Ferri,Giovanni B. Frisoni,Roberta Ghidoni,Carlo Miniussi,Guido Rodriguez,Gian Luca Romani,Rosanna Squitti,Maria Carla Ventriglia,Paolo Maria Rossini +15 more
TL;DR: The present multicentric EEG study tested the hypothesis that presence of ε4 affects sources of resting EEG rhythms in both MCI and AD subjects.
Journal ArticleDOI
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.
Julie van der Zee,Tim Van Langenhove,Gabor G. Kovacs,Lubina Dillen,William Deschamps,Sebastiaan Engelborghs,Radoslav Matěj,Mathieu Vandenbulcke,Anne Sieben,Bart Dermaut,Katrien Smets,Philip Van Damme,Céline Merlin,Annelies Laureys,Marleen Van den Broeck,Maria Mattheijssens,Karin Peeters,Luisa Benussi,Giuliano Binetti,Roberta Ghidoni,Barbara Borroni,Alessandro Padovani,Silvana Archetti,Pau Pastor,Pau Pastor,Cristina Razquin,Sara Ortega-Cubero,Sara Ortega-Cubero,Isabel Hernández,Mercè Boada,Agustín Ruiz,Alexandre de Mendonça,Gabriel Miltenberger-Miltenyi,Frederico Simões do Couto,Sandro Sorbi,Benedetta Nacmias,Silvia Bagnoli,Caroline Graff,Caroline Graff,Huei Hsin Chiang,Huei Hsin Chiang,Håkan Thonberg,Robert Perneczky,Robert Perneczky,Janine Diehl-Schmid,Panagiotis Alexopoulos,Giovanni B. Frisoni,Christian Bonvicini,Matthis Synofzik,Walter Maetzler,Jennifer Müller vom Hagen,Ludger Schöls,Tobias B. Haack,Tim M. Strom,Holger Prokisch,Oriol Dols-Icardo,Jordi Clarimón,Alberto Lleó,Isabel Santana,Maria Rosário Almeida,Beatriz Santiago,Michael T. Heneka,Frank Jessen,Alfredo Ramirez,Raquel Sánchez-Valle,Albert Lladó,Ellen Gelpi,Stayko Sarafov,Ivailo Tournev,Ivailo Tournev,Albena Jordanova,Eva Parobkova,Gian Maria Fabrizi,Silvia Testi,Eric Salmon,Thomas Ströbel,Patrick Santens,Wim Robberecht,Peter De Jonghe,Jean Jacques Martin,Patrick Cras,Rik Vandenberghe,Peter Paul De Deyn,Peter Paul De Deyn,Marc Cruts,Kristel Sleegers,Christine Van Broeckhoven +86 more
TL;DR: Investigation of the SQSTM1 coding sequence for mutations in an extended cohort of 1,808 patients with frontotemporal lobar degeneration showed that, comparable to other FTLD/ALS genes, SQ STM1 mutations are associated with TDP-43 pathology.
Journal ArticleDOI
The Mini-Mental State Examination in Alzheimer's disease and multi-infarct dementia.
Eugenio Magni,Giuliano Binetti,Alessandro Padovani,Stefano F. Cappa,Angelo Bianchetti,Marco Trabucchi +5 more
TL;DR: The data suggest that the MMSE may demonstrate a pattern of impairment of memory that differs between AD and MID, and possible explanations should take into account the different neuroanatomical impairments and the different degrees of motivation, due to depression or attentional deficits, toward external stimuli.