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Giuliano Binetti

Researcher at Sacred Heart Hospital

Publications -  250
Citations -  13455

Giuliano Binetti is an academic researcher from Sacred Heart Hospital. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 60, co-authored 234 publications receiving 11295 citations. Previous affiliations of Giuliano Binetti include Massachusetts Institute of Technology.

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Iron Serum Markers Profile in Frontotemporal Lobar Degeneration.

TL;DR: The significant decrease of the eCp/iCp in the FTLD patients supports the involvement of Fe imbalance in the onset and progression of FTLD.
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Contents Vol. 8, 2011

Jana Godau, +123 more
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P4-203: Full-length and not mature presenilin 2 increases the leakage of intracellular calcium stores: Specific mechanisms aand targets

TL;DR: It is suggested that, at variance with the majority of FL PS1 mutants that leave unchanged or even overload intracellular calcium stores, making the cells more susceptible to toxic stimuli, FL PS2 mutants by lowering ER/Golgi calcium levels result in a less aggressive FAD phenotypes.
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CCR5 deficiency: decreased neuronal resilience to oxidative stress and increased risk of vascular dementia.

TL;DR: In this article , the authors studied the link between CCR5 deficiency, the sensitivity of neurons to oxidative stress, and the development of dementia, and proposed the vulnerability of CCR-deficient neurons in response to oxidative stress as possible mechanisms contributing to dementia.
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Neuroanatomical correlates of screening for aphasia in NeuroDegeneration (SAND) battery in non-fluent/agrammatic variant of primary progressive aphasia

TL;DR: The authors investigated the neuroanatomical correlates of language deficits in primary progressive aphasia using verbal fluency tasks, AAChener Aphasie Test (AAT) naming subtest and SAND scores as proxies of brain structural imaging abnormalities.