G
Giuseppe Argiolas
Researcher at University of Sassari
Publications - 28
Citations - 860
Giuseppe Argiolas is an academic researcher from University of Sassari. The author has contributed to research in topics: Essential hypertension & Blood pressure. The author has an hindex of 16, co-authored 27 publications receiving 801 citations. Previous affiliations of Giuseppe Argiolas include University of Turin.
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Journal ArticleDOI
Adducin- and Ouabain-Related Gene Variants Predict the Antihypertensive Activity of Rostafuroxin, Part 2: Clinical Studies
Chiara Lanzani,Lorena Citterio,Nicola Glorioso,Paolo Manunta,Grazia Tripodi,Erika Salvi,Simona Delli Carpini,Mara Ferrandi,Elisabetta Messaggio,Jan A. Staessen,Jan A. Staessen,Daniele Cusi,Fabio Macciardi,Giuseppe Argiolas,Giovanni Valentini,Patrizia Ferrari,Bianchi Giuseppe,Bianchi Giuseppe +17 more
TL;DR: How an antihypertension drug can correct abnormal sodium pumping and how this understanding of the drug’s mechanism points to a genetic signature that can predict whether a patient will respond to the drug are described.
Journal ArticleDOI
Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase
Erika Salvi,Zoltán Kutalik,Nicola Glorioso,Paola Benaglio,Francesca Frau,Tatiana Kuznetsova,Hisatomi Arima,Clive J. Hoggart,Jean Tichet,Y Nikitin,Costanza Conti,Jitka Seidlerová,Valérie Tikhonoff,Katarzyna Stolarz-Skrzypek,Toby Johnson,Nabila Devos,Laura Zagato,Simonetta Guarrera,Roberta Zaninello,Andrea Calabria,Benedetta Stancanelli,Chiara Troffa,Lutgarde Thijs,Federica Rizzi,Galina Simonova,Sara Lupoli,Giuseppe Argiolas,Daniele Braga,Maria C. D'Alessio,Maria Francesca Ortu,Fulvio Ricceri,Maurizio Mercurio,Patrick Descombes,Maurizio Marconi,John Chalmers,Stephen B. Harrap,Jan Filipovsky,Murielle Bochud,Licia Iacoviello,Justine A. Ellis,Alice Stanton,Maris Laan,Sandosh Padmanabhan,Anna F. Dominiczak,Nilesh J. Samani,Olle Melander,Xavier Jeunemaitre,Paolo Manunta,Amnon Shabo,Paolo Vineis,Francesco P. Cappuccio,Mark J. Caulfield,Giuseppe Matullo,Carlo Rivolta,Patricia B. Munroe,Cristina Barlassina,Jan A. Staessen,Jacques S. Beckmann,Daniele Cusi +58 more
TL;DR: Biological evidence links endothelial NO synthase with hypertension, because it is a critical mediator of cardiovascular homeostasis and blood pressure control via vascular tone regulation, and the hypothesis that there may be a causal genetic variation at this locus is supported.
Journal ArticleDOI
α-Adducin 460Trp Allele Is Associated With Erythrocyte Na Transport Rate in North Sardinian Primary Hypertensives
Nicola Glorioso,Fabiana Filigheddu,Daniele Cusi,Chiara Troffa,Milena Conti,Marcella Natalizio,Giuseppe Argiolas,Cristina Barlassina,Giuseppe Bianchi +8 more
TL;DR: The hypothesis that the Gly460Trp &agr;-adducin polymorphism may affect renal Na handling through an alteration in ion transport across the cell membrane mirrored by erythrocytes is consistent with the hypothesis in humans.
Journal ArticleDOI
Genetic polymorphisms of the beta-adrenergic system: association with essential hypertension and response to beta-blockade.
Fabiana Filigheddu,Julia Reid,Chiara Troffa,P. Pinna-Parpaglia,Giuseppe Argiolas,A Testa,M Skolnick,Nicola Glorioso +7 more
TL;DR: Genetic polymorphisms of the β-adrenergic system: association with essential hypertension and response to β-blockade and impact on immune response are studied.
Journal ArticleDOI
Sardinians genetic background explained by runs of homozygosity and genomic regions under positive selection.
Cornelia Di Gaetano,Giovanni Fiorito,Maria Francesca Ortu,Fabio Rosa,Simonetta Guarrera,Barbara Pardini,Daniele Cusi,Francesca Frau,Cristina Barlassina,Chiara Troffa,Giuseppe Argiolas,Roberta Zaninello,Giovanni Fresu,Nicola Glorioso,Alberto Piazza,Giuseppe Matullo +15 more
TL;DR: The present study confirmed the high genetic homogeneity of Sardinia that may be explained by the shared ancestry combined with the action of evolutionary forces.