G
Guillaume Soubigou
Researcher at Pasteur Institute
Publications - 22
Citations - 2188
Guillaume Soubigou is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Gene & Endothelial stem cell. The author has an hindex of 17, co-authored 22 publications receiving 1971 citations.
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Journal ArticleDOI
The Listeria transcriptional landscape from saprophytism to virulence
Alejandro Toledo-Arana,Olivier Dussurget,Olivier Dussurget,Olivier Dussurget,Georgios Nikitas,Georgios Nikitas,Nina Sesto,Nina Sesto,Nina Sesto,Hélène Guet-Revillet,Hélène Guet-Revillet,Hélène Guet-Revillet,Damien Balestrino,Damien Balestrino,Damien Balestrino,Edmund Loh,Jonas Gripenland,Teresa Tiensuu,Karolis Vaitkevicius,Mathieu Barthelemy,Massimo Vergassola,Massimo Vergassola,Marie-Anne Nahori,Marie-Anne Nahori,Marie-Anne Nahori,Guillaume Soubigou,Béatrice Regnault,Jean-Yves Coppée,Marc Lecuit,Jörgen Johansson,Pascale Cossart,Pascale Cossart,Pascale Cossart +32 more
TL;DR: Using tiling arrays and RNAs from wild-type and mutant bacteria grown in vitro, ex vivo and in vivo, the transcription of its entire genome is analysed and it is discovered that riboswitches can act as terminators for upstream genes.
Journal ArticleDOI
Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin.
Steve P. Bernier,David Lebeaux,Alicia S. DeFrancesco,Amandine Valomon,Guillaume Soubigou,Jean-Yves Coppée,Jean-Marc Ghigo,Christophe Beloin +7 more
TL;DR: The results show that the SOS stress response induced in heterogeneous and nutrient-deprived biofilm microenvironments is a molecular mechanism leading to biofilm-specific high tolerance to the fluoroquinolone ofloxacin.
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A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.
Haig A. Eskandarian,Haig A. Eskandarian,Haig A. Eskandarian,Francis Impens,Marie-Anne Nahori,Marie-Anne Nahori,Marie-Anne Nahori,Guillaume Soubigou,Jean-Yves Coppée,Pascale Cossart,Pascale Cossart,Pascale Cossart,Melanie Hamon,Melanie Hamon,Melanie Hamon +14 more
TL;DR: The model bacterium Listeria monocytogenes is used and the mechanisms underlying a specific histone modification, deacetylation of histone H3 on lysine 18 (H3K18), are analyzed, showing that activity of SIRT2 is necessary for infection, both in vitro and in vivo.
Journal ArticleDOI
Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes
Sedigheh Delmaghani,Sedigheh Delmaghani,Sedigheh Delmaghani,Jean Defourny,Jean Defourny,Jean Defourny,Asadollah Aghaie,Asadollah Aghaie,Asadollah Aghaie,Maryline Beurg,Didier Dulon,Nicolas Thelen,Isabelle Perfettini,Isabelle Perfettini,Isabelle Perfettini,Tibor Zelles,Tibor Zelles,Máté Aller,Anaïs Meyer,Anaïs Meyer,Anaïs Meyer,Alice Emptoz,Alice Emptoz,Alice Emptoz,Fabrice Giraudet,Fabrice Giraudet,Michel Leibovici,Michel Leibovici,Michel Leibovici,Sylvie Dartevelle,Guillaume Soubigou,Marc Thiry,E. Sylvester Vizi,Saaid Safieddine,Saaid Safieddine,Saaid Safieddine,Jean Pierre Hardelin,Jean Pierre Hardelin,Jean Pierre Hardelin,Paul Avan,Paul Avan,Christine Petit +41 more
TL;DR: The results reveal that the antioxidant activity of peroxisomes protects the auditory system against noise-induced damage.
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Genome-Wide Analysis of Heteroduplex DNA in Mismatch Repair–Deficient Yeast Cells Reveals Novel Properties of Meiotic Recombination Pathways
Emmanuelle Martini,Valérie Borde,Valérie Borde,Matthieu Legendre,Stéphane Audic,Béatrice Regnault,Guillaume Soubigou,Bernard Dujon,Bertrand Llorente +8 more
TL;DR: It is observed that COs are associated with complex hDNA patterns, confirming that the canonical double-strand break repair model is not sufficient to explain the formation of most COs, and proposed that multiple factors contribute to the complexity of recombination intermediates.