H
Hanlin Zhang
Researcher at Chinese Academy of Sciences
Publications - 16
Citations - 634
Hanlin Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Brown adipose tissue & Thermogenin. The author has an hindex of 7, co-authored 16 publications receiving 368 citations. Previous affiliations of Hanlin Zhang include Anhui University.
Papers
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Journal ArticleDOI
Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue
Baoguo Li,Li Li,Min Li,Min Li,Sin Man Lam,Guanlin Wang,Guanlin Wang,Yingga Wu,Yingga Wu,Hanlin Zhang,Chaoqun Niu,Xueying Zhang,Xueying Zhang,Xue liu,Catherine Hambly,Wanzhu Jin,Guanghou Shui,John R. Speakman,John R. Speakman,John R. Speakman +19 more
TL;DR: Gavage of the bacterial metabolite butyrate increased the thermogenic capacity of ABX-treated mice, reversing the deficit and indicating that gut microbiota contributes to upregulated thermogenesis in the cold environment and that this may be partially mediated viabutyrate.
Journal ArticleDOI
Brown adipose tissue transplantation ameliorates polycystic ovary syndrome.
Xiaoxue Yuan,Tao Hu,Han Zhao,Han Zhao,Yuanyuan Huang,Rongcai Ye,Jun Lin,Chuanhai Zhang,Hanlin Zhang,Gang Wei,Huiqiao Zhou,Meng Dong,Jun Zhao,Jun Zhao,Haibin Wang,Qingsong Liu,Hyuek Jong Lee,Wanzhu Jin,Zi-Jiang Chen +18 more
TL;DR: It is shown that transplantation of brown adipose tissue (BAT) reversed anovulation, hyperandrogenism, and polycystic ovaries in a dehydroepiandrosterone (DHEA)-induced PCOS rat and that BAT activation might be a promising therapeutic option for the treatment of PCOS.
Journal ArticleDOI
Rutin ameliorates obesity through brown fat activation.
Xiaoxue Yuan,Gang Wei,Yilin You,Yuanyuan Huang,Hyuek Jong Lee,Meng Dong,Jun Lin,Tao Hu,Hanlin Zhang,Chuanhai Zhang,Huiqiao Zhou,Rongcai Ye,Xiao-Long Qi,Baiqiang Zhai,Weidong Huang,Shunai Liu,Wen Xie,Qingsong Liu,Xiaomeng Liu,Chengbi Cui,Donghao Li,Jicheng Zhan,Jun Cheng,Zengqiang Yuan,Wanzhu Jin +24 more
TL;DR: Rutin is a novel small molecule that activates BAT and may provide a novel therapeutic approach to the treatment of metabolic disorders and Rutin ameliorates obesity through brown fat activation.
Journal ArticleDOI
Myristoleic acid produced by enterococci reduces obesity through brown adipose tissue activation
Lin-Hu Quan,Chuanhai Zhang,Meng Dong,Jun Jiang,Hongde Xu,Chunlong Yan,Xiaomeng Liu,Huiqiao Zhou,Hanlin Zhang,Li Chen,Fei-Liang Zhong,Zhao-Bo Luo,Sin-Man Lam,Guanghou Shui,Donghao Li,Wanzhu Jin +15 more
TL;DR: The results demonstrated that the gut microbiota-LCFA-BAT axis plays an important role in host metabolism, which may provide a strategic advantage for the next generation of anti-obesity drug development.
Journal ArticleDOI
Brown adipose tissue activation by rutin ameliorates polycystic ovary syndrome in rat
Tao Hu,Xiaoxue Yuan,Rongcai Ye,Huiqiao Zhou,Jun Lin,Chuanhai Zhang,Hanlin Zhang,Gang Wei,Meng Dong,Yuanyuan Huang,Wonchung Lim,Qingsong Liu,Hyuek Jong Lee,Wanzhu Jin +13 more
TL;DR: It is found that 3 weeks of rutin (a novel compound for BAT activation) treatment increased BAT activation, thereby it improved thermogenesis and systemic insulin sensitivity in dehydroepiandrosterone (DHEA)-induced PCOS rat and surprisingly improved fertility and birth defect in PCOS rats.