Hans-Peter Lenhof

TL;DR: A Lamarckian genetic algorithm (LGA) variant for flexible ligand‐receptor docking which allows to handle a large number of degrees of freedom and may be used to dock ligands with many rotatable bonds with high efficiency.

TL;DR: This study provides strong evidence for miRNA expression signatures of blood cells as useful biomarkers for melanoma and finds that blood samples of melanoma patients and healthy individuals can be well differentiated from each other based on mi RNA expression analysis.

TL;DR: The presented use-case demonstrates that GeneTrail2 is well equipped for the integrative analysis of comprehensive -omics data and may help to shed light on complex pathogenic mechanisms in cancer and other diseases.

TL;DR: Multi-purpose, adjustable stabilizing cleats which can be attached to various types of transmission and/or drive shaft tunnel or hump mounted trays with adjustment of the cleats enabling them to be positioned for effective engagement with surface areas of transmission humps or tunnels of different shapes and configurations as discussed by the authors.

TL;DR: The findings support the idea that a developing lung cancer might be detectable years prior to diagnosis through a specific miRNA signature and that this signature changes during tumor development.