Hans Welzl

TL;DR: A critical role is demonstrated in the consolidation of enduring synaptic plasticity and memory storage in Arc/Arg3.1 knockout mice that fail to form long-lasting memories for implicit and explicit learning tasks, despite intact short-term memory.

TL;DR: It is demonstrated that inhibition of a specific glycine receptor subtype (GlyR α3) by PGE2-induced receptor phosphorylation underlies central inflammatory pain sensitization and may provide a previously unrecognized molecular target in pain therapy.

TL;DR: The results reveal an unexpected complexity of ERK-dependent signaling in the brain and a critical regulatory role for ERK1 in the long-term adaptive changes underlying striatum-dependent behavioral plasticity and drug addiction.

TL;DR: The data suggest that prenatal stress impairs spatial learning in males but not in females, and changes in corticosterone levels were altered in PS females and not in PS males; i.e., prenatal stress-induced changes in Corticosterone secretion were not paralleled by prenatal Stress-induced deficits in spatial learning.

TL;DR: The mutant mice show impaired learning of the water-maze task and deficits in measures of working memory on the radial maze due to behavioral perseverance and stereotypy, and show normal corticosterone levels at circadian trough and peak.