H
Harm Nijveen
Researcher at Wageningen University and Research Centre
Publications - 63
Citations - 4223
Harm Nijveen is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Population & Quantitative trait locus. The author has an hindex of 20, co-authored 56 publications receiving 3552 citations. Previous affiliations of Harm Nijveen include University of Groningen & Netherlands Bioinformatics Centre.
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Primer3Plus, an enhanced web interface to Primer3.
TL;DR: A new web interface to the popular Primer3 primer design program, developed in close collaboration with molecular biologists and technicians regularly designing primers, that provides an intuitive user interface using present-day web technologies and allows easy expansion or integration of external software packages.
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Learning from Co-expression Networks: Possibilities and Challenges
TL;DR: This study analyzes integrative genomics strategies used in recent studies that successfully identified candidate genes taking advantage of gene co-expression networks and discusses promising bioinformatics approaches that predict networks for specific purposes.
Journal Article
DNA polymorphisms and conditions for SSCP analysis of the 20 exons of the ret proto-oncogene.
Isabella Ceccherini,Robert M.W. Hofstra,Yin Luo,Rein P. Stulp,Barone,T. Stelwagen,Renata Bocciardi,Harm Nijveen,Bolino A,Marco Seri +9 more
TL;DR: To facilitate the screening for RET mutations, and to study possible genotype-phenotype correlations, exon-intron junctions were established and intronic sequences flanking the 20 exons of this gene were extended, making it possible to design primers and to develop PCR conditions useful for SSCP analysis of the whole RET coding sequence.
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Interaction between parental environment and genotype affects plant and seed performance in Arabidopsis
Hanzi He,Deborah de Souza Vidigal,L. Basten Snoek,Sabine K. Schnabel,Harm Nijveen,Henk W. M. Hilhorst,Leónie Bentsink,Leónie Bentsink +7 more
TL;DR: The genotype-by-environment interactions of five parental environments with seed and plant performance are mediated by distinct genetic and molecular pathways, and the selective pressures that have shaped their natural variation.
Journal ArticleDOI
Remarkably divergent regions punctuate the genome assembly of the Caenorhabditis elegans Hawaiian strain CB4856
Owen Thompson,L. Basten Snoek,Harm Nijveen,Mark G. Sterken,Rita J. M. Volkers,Rachel Brenchley,Arjen van 't Hof,Roel P. J. Bevers,Andrew R. Cossins,Itai Yanai,Alex Hajnal,Tobias Schmid,Jaryn D. Perkins,David H. Spencer,Leonid Kruglyak,Erik C. Andersen,Donald G. Moerman,LaDeana W. Hillier,Jan E. Kammenga,Robert H. Waterston +19 more
TL;DR: The draft sequence makes available a comprehensive catalog of sequence differences between the CB4856 and N2 strains that will facilitate the molecular dissection of their phenotypic differences, and emphasizes the importance of going beyond simple alignment of reads to a reference genome when assessing differences between genomes.