H
Heikki Lehväslaiho
Researcher at King Abdullah University of Science and Technology
Publications - 29
Citations - 5449
Heikki Lehväslaiho is an academic researcher from King Abdullah University of Science and Technology. The author has contributed to research in topics: Human genome & Genome. The author has an hindex of 19, co-authored 28 publications receiving 5187 citations. Previous affiliations of Heikki Lehväslaiho include European Bioinformatics Institute & South African National Bioinformatics Institute.
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Journal ArticleDOI
The Bioperl Toolkit: Perl Modules for the Life Sciences
Jason E. Stajich,David Block,David Block,Kris Boulez,Steven E. Brenner,Stephen A. Chervitz,Chris Dagdigian,Georg Fuellen,James G. R. Gilbert,Ian F Korf,Hilmar Lapp,Heikki Lehväslaiho,Chad Matsalla,Christopher J. Mungall,Brian I. Osborne,Matthew Pocock,Peter Schattner,Martin Senger,Lincoln Stein,Elia Stupka,Mark Wilkinson,Ewan Birney +21 more
TL;DR: The overall architecture of the Bioperl toolkit is described, the problem domains that it addresses, and specific examples of how the toolkit can be used to solve common life-sciences problems are given.
Journal ArticleDOI
The Ensembl genome database project
Tim Hubbard,Daniel Barker,Ewan Birney,Graham Cameron,Yuan Chen,Louise Clark,Tony Cox,James Cuff,Val Curwen,Thomas A. Down,Richard Durbin,Eduardo Eyras,James G. R. Gilbert,Martin Hammond,Lukasz Huminiecki,Arek Kasprzyk,Heikki Lehväslaiho,Philip Lijnzaad,Craig Melsopp,Emmanuel Mongin,Roger Pettett,Matthew Pocock,Simon C. Potter,Alistair G. Rust,Esther Schmidt,Stephen M. J. Searle,Guy Slater,James Smith,William Spooner,Arne Stabenau,Jim Stalker,Elia Stupka,Abel Ureta-Vidal,Imre Vastrik,Michele Clamp +34 more
TL;DR: The Ensembl database project provides a bioinformatics framework to organise biology around the sequences of large genomes and is a comprehensive source of stable automatic annotation of the human genome sequence, with confirmed gene predictions that have been integrated with external data sources.
Journal ArticleDOI
An Overview of Ensembl
Ewan Birney,T. Daniel Andrews,Paul Bevan,Mario Caccamo,Yuan Chen,Laura Clarke,Guy Coates,James Cuff,Val Curwen,Tim J.R. Cutts,Thomas A. Down,Eduardo Eyras,Xosé M. Fernández-Suárez,Paul Gane,Brian Gibbins,James G. R. Gilbert,Martin Hammond,Hans-Rudolf Hotz,Vivek Iyer,Kerstin Jekosch,Andreas Kähäri,Arek Kasprzyk,Damian Keefe,Stephen Keenan,Heikki Lehväslaiho,Graham McVicker,Craig Melsopp,Patrick Meidl,Emmanuel Mongin,Roger Pettett,Simon C. Potter,Glenn Proctor,Mark Rae,Steve Searle,Guy Slater,Damian Smedley,James Smith,William Spooner,Arne Stabenau,James Stalker,Roy Storey,Abel Ureta-Vidal,K. Cara Woodwark,Graham Cameron,Richard Durbin,Anthony J. Cox,Tim Hubbard,Michele Clamp +47 more
TL;DR: The aims of Ensembl are to "widen" this biological integration to include other model organisms relevant to understanding human biology as they become available; to "deepen" this integration to provide an ever more seamless linkage between equivalent components in different species; and to provide further classification of functional elements in the genome that have been previously elusive.
Journal ArticleDOI
The Androgen Receptor Gene Mutations Database
Bruce Gottlieb,Heikki Lehväslaiho,Lenore K. Beitel,Rose Lumbroso,Leonard Pinsky,Mark Trifiro,Mark Trifiro +6 more
TL;DR: The current version of the androgen receptor (AR) gene mutations database is described, and the contribution of CpG sites to the multiplicity of reports of the same mutation in different families is examined.
Journal ArticleDOI
Ensembl 2002: accommodating comparative genomics
Michele Clamp,D. Andrews,Daniel Barker,Paul Bevan,Graham Cameron,Yuan Chen,Louise Clark,Tony Cox,James Cuff,Val Curwen,Thomas A. Down,Richard Durbin,Eduardo Eyras,James G. R. Gilbert,Martin Hammond,Tim Hubbard,Arek Kasprzyk,Damian Keefe,Heikki Lehväslaiho,Vivek Iyer,Craig Melsopp,Emmanuel Mongin,Roger Pettett,Simon C. Potter,Alistair G. Rust,Esther Schmidt,S. Searle,Guy Slater,James Smith,William Spooner,Arne Stabenau,Jim Stalker,Elia Stupka,Abel Ureta-Vidal,Imre Vastrik,Ewan Birney +35 more
TL;DR: The Ensembl database project provides a bioinformatics framework to organise biology around the sequences of large genomes, a comprehensive source of stable automatic annotation of human, mouse and other genome sequences, available as either an interactive web site or as flat files.