H
Hilde Dannenberg
Researcher at Erasmus University Rotterdam
Publications - 11
Citations - 893
Hilde Dannenberg is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Germline mutation & SDHD. The author has an hindex of 10, co-authored 11 publications receiving 847 citations.
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Journal ArticleDOI
An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.
Francien H van Nederveen,José Gaal,Judith Favier,Esther Korpershoek,Rogier A. Oldenburg,Elly M C A de Bruyn,Hein F.B.M. Sleddens,Pieter Derkx,Julie Rivière,Hilde Dannenberg,Bart-Jeroen Petri,Paul Komminoth,Karel Pacak,Wim C. J. Hop,Patrick J. Pollard,Massimo Mannelli,Jean-Pierre Bayley,Aurel Perren,Stephan Niemann,Albert A.J. Verhofstad,Adriaan P. de Bruïne,Eamonn R. Maher,Frédérique Tissier,Tchao Meatchi,Cécile Badoual,Jérôme Bertherat,Laurence Amar,Despoina Alataki,Eric Van Marck,Francesco Ferraù,Jerney François,Wouter W. de Herder,Mark-Paul F M Vrancken Peeters,Anne van Linge,Jacques W.M. Lenders,Jacques W.M. Lenders,Anne-Paule Gimenez-Roqueplo,Ronald R. de Krijger,Winand N.M. Dinjens +38 more
TL;DR: Phaeochromocytoma-paraganglioma syndrome can be diagnosed reliably by an immunohistochemical procedure and SDHB immunohistsochemistry could improve the diagnosis, according to a large retrospective and prospective tumour series.
Journal ArticleDOI
Losses of chromosomes 1p and 3q are early genetic events in the development of sporadic pheochromocytomas.
Hilde Dannenberg,Ernst J. M. Speel,Jianming Zhao,Parvin Saremaslani,Erwin van der Harst,Jürgen Roth,Philipp U. Heitz,H. Jaap Bonjer,Winand N.M. Dinjens,Wolter J. Mooi,Paul Komminoth,Ronald R. de Krijger +11 more
TL;DR: The results suggest that the development of pheochromocytomas is associated with specific genomic aberrations, such as losses of 1p, 3q, and 6q and gains of 9q and 17q and aneuploidy in some tumors.
Journal Article
Frequent germ-line succinate dehydrogenase subunit D gene mutations in patients with apparently sporadic parasympathetic paraganglioma.
Hilde Dannenberg,Winand N.M. Dinjens,Mustaffa Abbou,Hero van Urk,Bernard K. H. Pauw,Diane Mouwen,Wolter J. Mooi,Ronald R. de Krijger +7 more
TL;DR: Germ-line mutations of the SDHD gene are present in a significant number of patients with apparently sporadic parasympathetic PGL, and somatic SDHD mutations do not play a significant role in the sporadic form of this tumor.
Journal ArticleDOI
Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas
Hilde Dannenberg,Ronald R. de Krijger,Erwin van der Harst,Mustaffa Abbou,Ynske IJzendoorn,Paul Komminoth,Winand N.M. Dinjens +6 more
TL;DR: No distinction in the nature of VHL alterations between benign and malignant pheochromocytomas and no correlation with histopathologic or clinical features was observed and it is reported that VHL mutations may have some impact on the malignant transformation of p heochromoctomas.
Journal ArticleDOI
Microarray-based CGH of sporadic and syndrome-related pheochromocytomas using a 0.1-0.2 Mb bacterial artificial chromosome array spanning chromosome arm 1p.
Marieke Aarts,Hilde Dannenberg,Ronald J. deLeeuw,Francien H van Nederveen,Albert A.J. Verhofstad,Jacques W.M. Lenders,Winand N.M. Dinjens,Ernst-Jan M. Speel,Wan L. Lam,Ronald R. de Krijger +9 more
TL;DR: Data strongly suggest that chromosome arm 1p is the site for multiple tumor suppressor genes, although the potential candidate genes CDKN2C and PTPRF/LAR are not included in these regions.