H
Hirotomo Kato
Researcher at Jichi Medical University
Publications - 143
Citations - 3958
Hirotomo Kato is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Cutaneous leishmaniasis & Leishmania. The author has an hindex of 32, co-authored 135 publications receiving 3567 citations. Previous affiliations of Hirotomo Kato include Tokyo Medical and Dental University & Hokkaido University.
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Journal ArticleDOI
Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.
M Hijikata,Yohko K. Shimizu,Hirotomo Kato,Aikichi Iwamoto,J. W. Shih,H J Alter,Robert H. Purcell,Hiroshi Yoshikura +7 more
TL;DR: Examination of serial sera from a chimpanzee infected with HCV revealed parallel changes in the buoyant density and immunoprecipitability of HCV-associated RNA during the course of infection, suggesting that HCV is bound to anti-HCV antibodies as antigen-antibody complexes in chronic hepatitis C.
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Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax.
Tomonori Tsukahara,Mari Kannagi,Takashi Ohashi,Hirotomo Kato,Masaaki Arai,Gabriel Núñez,Youichi Iwanaga,Naoki Yamamoto,Kiyoshi Ohtani,Masataka Nakamura,Masahiro Fujii +10 more
TL;DR: The findings suggest that constitutive expression of Bcl-xL induced by Tax through the NF-κB pathway contributes to the inhibition of apoptosis in CTLL-2 cells after IL-2 deprivation.
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Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region
Maria E. Grillet,Juan V Hernández-Villena,Martin S. Llewellyn,Alberto Paniz-Mondolfi,Adriana Tami,Adriana Tami,Maria F. Vincenti-Gonzalez,Marilianna Marquez,Adriana C Mogollon-Mendoza,Carlos E. Hernandez-Pereira,Juan D Plaza-Morr,Gabriella Blohm,Gabriella Blohm,Mario J. Grijalva,Jaime A. Costales,Heather M. Ferguson,Philipp Schwabl,Luis E. Hernandez-Castro,Poppy H. L. Lamberton,Daniel G. Streicker,Daniel T. Haydon,Michael A. Miles,Alvaro Acosta-Serrano,Harry Acquattela,Maria G Basañez,Gustavo Benaim,Luis A Colmenares,Jan E. Conn,Jan E. Conn,Raul Espinoza,Héctor Freilij,Mary C Graterol-Gil,Peter J. Hotez,Hirotomo Kato,John A. Lednicky,Clara Martínez,Santiago Mas-Coma,J Glen Morris,Juan Carlos Navarro,José Luis Ramírez,Marlenes Rodríguez,Julio A. Urbina,Leopoldo Villegas,Maikell Segovia,Hernán J. Carrasco,James Lee Crainey,Sérgio Luiz Bessa Luz,Juan D Moreno,Oscar Noya González,Juan David Ramírez,Belkisyolé Alarcón de Noya +50 more
TL;DR: The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts, and national, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders.
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Detection and identification of leishmania species within naturally infected sand flies in the andean areas of ecuador by a polymerase chain reaction
Hirotomo Kato,Hiroshi Uezato,Ken Katakura,Manuel Calvopiña,Jorge Diego Marco,Paola Andrea Barroso,Eduardo A. Gomez,Tatsuyuki Mimori,Masataka Korenaga,Hiroyuki Iwata,Shigeo Nonaka,Yoshihisa Hashiguchi +11 more
TL;DR: A polymerase chain reaction (PCR)-based method for detection of Leishmania minicircle DNA within individual sand flies, which will be a powerful tool for the rapid identification of prevalent sand fly and Leishmaniasis species as well as monitoring the infection rate in sand fly populations in endemic areas.
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Evidence For Early Aging in the Mucosal Immune System
TL;DR: These results provide the first evidence that the development of age-associated alterations possibly occurs earlier in the mucosal immune system than in the systemic immune compartment.