H
Hyoung-Gon Ko
Researcher at Kyungpook National University
Publications - 20
Citations - 974
Hyoung-Gon Ko is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Synaptic plasticity & Long-term potentiation. The author has an hindex of 10, co-authored 19 publications receiving 806 citations. Previous affiliations of Hyoung-Gon Ko include UPRRP College of Natural Sciences & Xi'an Jiaotong University.
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Journal ArticleDOI
Alleviating Neuropathic Pain Hypersensitivity by Inhibiting PKMζ in the Anterior Cingulate Cortex
Xiang-Yao Li,Xiang-Yao Li,Hyoung-Gon Ko,Tao Chen,Tao Chen,Giannina Descalzi,Kohei Koga,Hansen Wang,Susan S. Kim,Yuze Shang,Chuljung Kwak,Soowon Park,Jaehoon Shim,Jaehoon Shim,Kyungmin Lee,Kyungmin Lee,Graham L. Collingridge,Graham L. Collingridge,Bong-Kiun Kaang,Bong-Kiun Kaang,Min Zhuo,Min Zhuo +21 more
TL;DR: It is found that protein kinase M zeta (PKMζ) maintains pain-induced persistent changes in the mouse anterior cingulate cortex (ACC) and could be a new therapeutic target for treating chronic pain.
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Interregional synaptic maps among engram cells underlie memory formation
Jun-Hyeok Choi,Su-Eon Sim,Ji-il Kim,Dong Il Choi,Jihae Oh,Sanghyun Ye,Jaehyun Lee,Tae Hyun Kim,Hyoung-Gon Ko,Chae-Seok Lim,Bong-Kiun Kaang +10 more
TL;DR: The dual-eGRASP (green fluorescent protein reconstitution across synaptic partners) technique was developed to examine synapses between engram cells to identify the specific neuronal site for memory storage and found an increased number and size of spines.
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Induction of Neuronal Vascular Endothelial Growth Factor Expression by cAMP in the Dentate Gyrus of the Hippocampus Is Required for Antidepressant-Like Behaviors
Jeong-Sik Lee,Deok-Jin Jang,Nuribalhae Lee,Hyoung-Gon Ko,Hyoung F. Kim,Yong-Seok Kim,Byung-Woo Kim,Junehee Son,Sunghyun Kim,Heekyoung Chung,Mun-Yong Lee,Woon Ryoung Kim,Woong Sun,Min Zhuo,Ted Abel,Bong-Kiun Kaang,Hyeon Son +16 more
TL;DR: A molecular interaction between the cAMP cascade and VEGF expression is revealed, and the pronounced behavioral consequences of this interaction shed light on the mechanism underlying neuronal V EGF functions in antidepression.
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Plasticity of Metabotropic Glutamate Receptor-Dependent Long-Term Depression in the Anterior Cingulate Cortex after Amputation
Sukjae Joshua Kang,Ming-Gang Liu,Tao Chen,Hyoung-Gon Ko,Gi-Chul Baek,Hye-Ryeon Lee,Kyungmin Lee,Graham L. Collingridge,Graham L. Collingridge,Bong-Kiun Kaang,Min Zhuo,Min Zhuo +11 more
TL;DR: It is demonstrated that tail amputation causes LTD impairment within the ACC circuit and that this can be rescued by activation of mGluR1, a form of metaplasticity that involved the activation of protein kinase C.
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A new, iterative strategy for the synthesis of unsymmetrical polyynes: application to the total synthesis of 15,16-dihydrominquartynoic acid.
TL;DR: The utility of this new iterative strategy for the synthesis of unsymmetrically substituted polyynes is demonstrated by its application to the total synthesis of (S)-(E)-15,16-dihydrominquartynoic acid.