I
Ian Gilron
Researcher at Queen's University
Publications - 223
Citations - 13522
Ian Gilron is an academic researcher from Queen's University. The author has contributed to research in topics: Chronic pain & Clinical trial. The author has an hindex of 49, co-authored 200 publications receiving 11203 citations. Previous affiliations of Ian Gilron include McGill University & Harvard University.
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Journal ArticleDOI
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.
Nanna B. Finnerup,Nadine Attal,Simon Haroutounian,Ewan D McNicol,Ralf Baron,Robert H. Dworkin,Ian Gilron,Maija Haanpää,Per Hansson,Per Hansson,Troels S. Jensen,Troels S. Jensen,Peter R. Kamerman,Karen Lund,Andrew Moore,Srinivasa N. Raja,Andrew S.C. Rice,Andrew S.C. Rice,Michael C. Rowbotham,Emily S. Sena,Emily S. Sena,Philip J. Siddall,Philip J. Siddall,Blair H. Smith,Mark S. Wallace +24 more
TL;DR: The results support a revision of the NeuPSIG recommendations for the pharmacotherapy of neuropathic pain and allow a strong recommendation for use and proposal as first-line treatment in neuropathicPain for tricyclic antidepressants, serotonin-noradrenaline reuptake inhibitors, pregabalin, and gabapentin.
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Morphine, Gabapentin, or Their Combination for Neuropathic Pain
TL;DR: Gabapentin and morphine combined achieved better analgesia at lower doses of each drug than either as a single agent, with constipation, sedation, and dry mouth as the most frequent adverse effects.
Journal ArticleDOI
Pharmacological Management of Chronic Neuropathic Pain – Consensus Statement and Guidelines from the Canadian Pain Society
Dwight E. Moulin,Alexander J. Clark,Ian Gilron,Mark A. Ware,CP Watson,Barry J. Sessle,Terence J. Coderre,Patricia Morley-Forster,Jennifer Stinson,Aline Boulanger,Philip Peng,GA Finley,Paul Taenzer,P Squire,Dominique Dion,A Cholkan,Anwarul Hassan Gilani,Allan Gordon,James L. Henry,Roman D. Jovey,M Lynch,A Mailis-Gagnon,Akbar Panju,GB Rollman,Ana M. Velly +24 more
TL;DR: Randomized, controlled trials, systematic reviews and existing guidelines focusing on the pharmacological management of NeP were evaluated at a consensus meeting and recommendations for treatment are based on degree of evidence of analgesic efficacy, safety, ease of use and cost-effectiveness.
Journal ArticleDOI
Neuropathic pain: a practical guide for the clinician
TL;DR: A primary care algorithm for treatments with the most favourable risk–benefit profile is proposed, including topical lidocaine, gabapentin, pregabalin, tricyclic antidepressants, mixed serotonin–norepinephrine reuptake inhibitors, tramadol and opioids.
Journal ArticleDOI
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial
Ian Gilron,Ian Gilron,Joan M. Bailey,Joan M. Bailey,Dongsheng Tu,Ronald R. Holden,Alan Jackson,Robyn L. Houlden,Robyn L. Houlden +8 more
TL;DR: Combined gabapentin and nortriptyline seems to be more efficacious than either drug given alone for neuropathic pain, therefore it is recommended to use this combination in patients who show a partial response to either druggiven alone and seek additional pain relief.