Ikuo Miura

TL;DR: Two dominant mutations that affect sleep and wakefulness are identified by using an electroencephalogram/electromyogram-based screen of randomly mutagenized mice and the role of SIK3 and NALCN in regulating the amount of NREMS and REMS is demonstrated.

TL;DR: The bearded dragon, Pogona vitticeps, has differentiated previously unidentifable W and Z micro-sex chromosomes, the first to be demonstrated in an agamid lizard, implying that heterochromatinization of the heterogametic chromosome occurred during sex chromosome differentiation in this species.

TL;DR: The impact of germline mutation rates on phenotypes in a mammalian population is revealed and fundamental information about mouse genetics is provided and the impact of mutation accumulation on phenotype is revealed.

TL;DR: There is evidence that the male heterogametic sex determination of the frog Rana rugosa returned to its previous female state during speciation that occurred when the distribution range of the frogs expanded across Japan, quite recent in the phylogenetic time scale.

TL;DR: A very high rate of sex chromosome turnover in true frogs is shown, which may be driven by rapid mutation-load accumulation due to the low recombination rate in males, suggesting a key role for mutation- load accumulation in non-recombining genomic regions.