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Irina Pugach
Researcher at Max Planck Society
Publications - 21
Citations - 1730
Irina Pugach is an academic researcher from Max Planck Society. The author has contributed to research in topics: Population & Genetic admixture. The author has an hindex of 12, co-authored 19 publications receiving 1458 citations.
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Journal ArticleDOI
Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania
David Reich,Nick Patterson,Martin Kircher,Frederick C. Delfin,Madhusudan R. Nandineni,Irina Pugach,Albert Min-Shan Ko,Ying-Chin Ko,Timothy A. Jinam,Maude E. Phipps,Naruya Saitou,Andreas Wollstein,Andreas Wollstein,Manfred Kayser,Svante Pääbo,Mark Stoneking +15 more
TL;DR: The results indicate that Denisova gene flow occurred into the common ancestors of New Guineans, Australians, and Mamanwa but not into the ancestors of the Jehai and Onge and suggest that relatives of present-day East Asians were not in Southeast Asia when the DenisovaGene flow occurred.
Journal ArticleDOI
A genomic history of Aboriginal Australia
Anna-Sapfo Malaspinas,Anna-Sapfo Malaspinas,Anna-Sapfo Malaspinas,Michael C. Westaway,Craig Muller,Vitor C. Sousa,Vitor C. Sousa,Oscar Lao,Isabel Alves,Isabel Alves,Isabel Alves,Anders Bergström,Georgios Athanasiadis,Jade Yu Cheng,Jade Yu Cheng,Jacob E. Crawford,Tim H. Heupink,Enrico Macholdt,Stephan Peischl,Stephan Peischl,Simon Rasmussen,Stephan Schiffels,Sankar Subramanian,Joanne L. Wright,Anders Albrechtsen,Chiara Barbieri,Isabelle Dupanloup,Isabelle Dupanloup,Anders Eriksson,Anders Eriksson,Ashot Margaryan,Ida Moltke,Irina Pugach,Thorfinn Sand Korneliussen,Ivan P. Levkivskyi,J. Víctor Moreno-Mayar,Shengyu Ni,Fernando Racimo,Martin Sikora,Yali Xue,Farhang Aghakhanian,Nicolas Brucato,Søren Brunak,Paula F. Campos,Paula F. Campos,Warren Clark,Sturla Ellingvåg,Gudjugudju Fourmile,Pascale Gerbault,Darren Injie,George Koki,Matthew Leavesley,Betty Logan,Aubrey Lynch,Elizabeth Matisoo-Smith,Peter McAllister,Alexander J. Mentzer,Mait Metspalu,Andrea Bamberg Migliano,Les Murgha,Maude E. Phipps,William Pomat,Doc Reynolds,François-Xavier Ricaut,Peter Siba,Mark G. Thomas,Thomas Wales,Colleen Ma Run Wall,Stephen Oppenheimer,Chris Tyler-Smith,Richard Durbin,Joe Dortch,Andrea Manica,Mikkel H. Schierup,Robert Foley,Robert Foley,Marta Mirazón Lahr,Marta Mirazón Lahr,Claire Bowern,Jeffrey D. Wall,Thomas Mailund,Mark Stoneking,Rasmus Nielsen,Rasmus Nielsen,Manjinder S. Sandhu,Laurent Excoffier,Laurent Excoffier,David M. Lambert,Eske Willerslev,Eske Willerslev,Eske Willerslev +90 more
TL;DR: A population expansion in northeast Australia during the Holocene epoch associated with limited gene flow from this region to the rest of Australia, consistent with the spread of the Pama–Nyungan languages is inferred.
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Genetic variation and recent positive selection in worldwide human populations: evidence from nearly 1 million SNPs.
David López Herráez,Marc Bauchet,Kun Tang,Christoph Theunert,Irina Pugach,Jing Li,Madhusudan R. Nandineni,Arnd Gross,Markus Scholz,Mark Stoneking +9 more
TL;DR: Two genes involved in the thyroid hormone pathway that show signals of selection in African Pygmies that may be related to their short stature are identified.
Journal ArticleDOI
Genome-wide data substantiate Holocene gene flow from India to Australia
TL;DR: An ancient association is found between Australia, New Guinea, and the Mamanwa (a Negrito group from the Philippines), with divergence times for these groups estimated at 36,000 y ago, supporting the view that these populations represent the descendants of an early “southern route” migration out of Africa, whereas other populations in the region arrived later by a separate dispersal.
Journal ArticleDOI
Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation
Jarosław Bryk,Emilie A. Hardouin,Irina Pugach,David A. Hughes,Rainer Strotmann,Mark Stoneking,Sean Myles +6 more
TL;DR: Evidence is presented that a derived nonsynonymous substitution (370A) in EDAR, a gene involved in ectodermal development, was driven to high frequency in East Asia by positive selection prior to 10,000 years ago.