I
Iskren Kotzev
Researcher at Medical University of Varna
Publications - 21
Citations - 1878
Iskren Kotzev is an academic researcher from Medical University of Varna. The author has contributed to research in topics: Liver biopsy & Medicine. The author has an hindex of 7, co-authored 20 publications receiving 1720 citations.
Papers
More filters
Journal ArticleDOI
Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
Patrick Marcellin,E. Jenny Heathcote,Maria Buti,Edward Gane,Robert A. de Man,Zahary Krastev,George Germanidis,Sam Lee,Robert Flisiak,Kelly Kaita,Michael P. Manns,Iskren Kotzev,Konstantin Tchernev,Peter Buggisch,Frank Weilert,Oya Ovung Kurdas,Mitchell L. Shiffman,Huy N. Trinh,Mary Kay Washington,Jeff Sorbel,Jane Anderson,Andrea Snow-Lampart,Elsa Mondou,Joseph B. Quinn,Franck Rousseau +24 more
TL;DR: Among patients with chronic HBV infection, tenofovir DF at a daily dose of 300 mg had superior antiviral efficacy with a similar safety profile as compared with adefovir dipivoxil at adaily dose of 10 mg through week 48.
Journal ArticleDOI
Three-Year Efficacy and Safety of Tenofovir Disoproxil Fumarate Treatment for Chronic Hepatitis B
E. Jenny Heathcote,Patrick Marcellin,Maria Buti,Edward Gane,Robert A. de Man,Zahary Krastev,George Germanidis,Samuel S. Lee,Robert Flisiak,Kelly Kaita,Michael P. Manns,Iskren Kotzev,Konstantin Tchernev,Peter Buggisch,Frank Weilert,Oya Ovunc Kurdas,Mitchell L. Shiffman,Huy N. Trinh,Selim Gürel,Andrea Snow–Lampart,Katyna Borroto–Esoda,Elsa Mondou,J. Anderson,Jeff Sorbel,Franck Rousseau +24 more
TL;DR: TDF was safe and effective in the long-term management of H beAg(+) and HBeAg(-) patients with chronic hepatitis B and maintained a favorable safety profile for up to 3 years.
Journal ArticleDOI
Hepatitis C virus prevalence and level of intervention required to achieve the WHO targets for elimination in the European Union by 2030: a modelling study
Homie Razavi,Sarah Robbins,Stefan Zeuzem,Francesco Negro,Maria Buti,Ann-Sofi Duberg,Françoise Roudot-Thoraval,Antonio Craxì,Michael Manns,Rui Tato Marinho,Béla Hunyady,Massimo Colombo,Soo Aleman,Krasimir Antonov,Perttu Arkkila,Kostas Athanasakis,Sarah Blach,M. Blachier,Antonio Javier Blasco,Filipe Calinas,Jose Luis Calleja,Peer Brehm Christensen,Matthew E. Cramp,E. A. Croes,Robert J. de Knegt,Victor de Ledinghen,Jean-Michel Delile,Chris Estes,Karolin Falconer,Martti Färkkilä,Robert Flisiak,Sona Frankova,Ivane Gamkrelidze,Javier García-Samaniego,Jordan Genov,Jan Gerstoft,Liana Gheorghe,Adrian Goldis,Ilias Gountas,Sergeja Gregorčič,Michael Gschwantler,Jessie Gunter,Waldemar Halota,Laura Harcouet,Christophe Hézode,Patrick Hoffmann,Gabor Horvath,Irena Hrstić,Peter Jarcuska,Deian Jelev,Agita Jeruma,Martin Kåberg,Jennifer Kieran,Loreta A. Kondili,Iskren Kotzev,Henrik Krarup,Pavol Kristian,Martin Lagging,Wim Laleman,Pablo Lázaro,Valentina Liakina,Boris Lukšić,Matti Maimets,Mihály Makara,Lyudmila Mateva,Mojca Matičič,Francesco Saverio Mennini,Rumiana Mitova,Christophe Moreno,Joël Mossong,Kimberly Murphy,Helen Nde,Vratislav Nemecek,Dijana Nonkovic,Suzanne Norris,Marian Oltman,Anne Øvrehus,George V. Papatheodoridis,Ken Pasini,Devin Razavi-Shearer,Kathryn Razavi-Shearer,Henk W. Reesink,Tatjana Reic,Baiba Rozentale,Stephen D. Ryder,Riina Salupere,Rui Sarmento-Castro,Christoph Sarrazin,Jonathan Schmelzer,Ivan Schréter,Carole Seguin-Devaux,Kaarlo Simojoki,Marietta Simonova,Peter J Smit,Kyriakos Souliotis,Danute Speiciene,Jan Sperl,Peter Stärkel,Daniel Struck,Vana Sypsa,Lelia Thornton,Ieva Tolmane,Krzysztof Tomasiewicz,Jonas Valantinas,Pierre Van Damme,David A. M. C. van de Vijver,Adriaan J. van der Meer,Daniela K van Santen,Hans Van Vlierberghe,Dominique Vandijck,Stefano Vella,Jerneja Videčnik-Zorman,Wolfgang Vogel,Nina Weis,Angelos Hatzakis +114 more
TL;DR: The EU is uniquely poised to eliminate HCV; however, expansion of screening programmes is essential to increase treatment to achieve the WHO targets, and a united effort, grounded in sound epidemiological evidence, will also be necessary.
Journal ArticleDOI
Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in treatment of chronic hepatitis B.
Seng Gee Lim,Zahary Krastev,Tay Meng Ng,Grigor Mechkov,Iskren Kotzev,Sing Chan,Elsa Mondou,Andrea Snow,Jeff Sorbel,Franck Rousseau +9 more
TL;DR: After 24 weeks of treatment, no significant difference between arms was observed, but there was a significantly greater virologic and biochemical response 24 weeks posttreatment in the FTC+CLV arm.
Journal ArticleDOI
Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial
Bruce E. Sands,Peter M. Irving,T. C. Hoops,James L. Izanec,Long Long Gao,Christopher Gasink,Andrew Greenspan,Matthieu Allez,Silvio Danese,Stephen B. Hanauer,Vipul Jairath,Tanja Kuehbacher,James D. Lewis,Edward V. Loftus,Remo Panaccione,Ellen Scherl,William J. Sandborn,Anita Afzali,L R Aitova,Xavier Aldeguer Manté,István Altorjay,F Argüelles Arias,Alessandro Armuzzi,Monika Augustyn,M. Bafutto,Jesus Barrio,Jakob Begun,Clint E Behrend,G. Bezemer,Guillaume Bonnaud,Marija Branković,Ik Jang Byung,Xavier Calvet Calvo,Karen A. Chachu,Julio Maria Fonseca Chebli,Jae Hee Cheon,Halina Cichoż-Lach,Larry E. Clark,Fraser Cummings,Kunal K Dalal,Nanne K. H. de Boer,Maria de Lourdes Abreu Ferrari,Etienne Desilets,Predrag Dugalic,G. Aaron DuVall,O. V. Fedorishina,Rafał Filip,Cristina Flores,Ronald Fogel,James Fon,Michael S. Frankel,Keith Friedenberg,Walter Fries,V Denisova Galina,Piotr Gietka,Rishi M Goel,Peter Hasselblatt,Hans H Herfarth,László Herszényi,Pieter Hindryckx,Frank Hoentjen,Carmen S Horjus Talabur Horje,Satish Iduru,Robert J. Isfort,Michael P. Jones,D. Kh. Kalimullina,Jeff Katz,Manreet Kaur,Sunil Khurana,Joo Sung Kim,Youngho Yungho Kim,Dariusz Kleczkowski,Slavko Knezevic,Aaron Knoll,Louis Y. Korman,Iskren Kotzev,A.V. Kulyapin,Kang Moon Lee,D. Leemreis,Jaroslaw Leszczyszyn,Jimmy K. Limdi,Jack J. Lissauer,Ewa Małecka-Panas,John Marshall,Emese Mihály,Lukas Milan,Giovanni Monteleone,Aleksandar Nagorni,Danuta Owczarek,Nichole Palekar,Young Soo Park,Sang Hyoung Park,Rogério Serafim Parra,Árpád V. Patai,Kamal V. Patel,Bhaktasharan Patel,A.A. Pershko,Elina Petrova,Guillaume Pineton de Chambrun,C. Randall,Sabino Riestra Menéndez,Timothy L. Ritter,Montserrat Rivero,Xavier Roblin,Rodolfo Rocca,Jacek Romatowski,Grażyna Rydzewska,Simone Saibeni,Bruce Salzberg,H.L. Sarles,John Saunders,Edoardo Savarino,Zuzana Serclova,O. B. Shchukina,Jonathan H. Siegel,Najm M. Soofi,Miles P. Sparrow,D Stokesberry,Daniel R. Suiter,Petar Svorcan,Alexander Tkachev,Nikolay Tsonev,Kristóf Tünde,Jan Ulbrych,Tomas Vanasek,Márta Varga,Severine Vermeire,Raquel Vicente Lidón,Michael L Weiss,Emma Wesley,Nathaniel S. Winstead,Katarzyna Wójcik,Joanna Wypych,Cyrla Zaltman,Zadorova Zdena +134 more