E
Ellen Scherl
Researcher at Cornell University
Publications - 194
Citations - 6384
Ellen Scherl is an academic researcher from Cornell University. The author has contributed to research in topics: Inflammatory bowel disease & Medicine. The author has an hindex of 36, co-authored 147 publications receiving 4768 citations. Previous affiliations of Ellen Scherl include NewYork–Presbyterian Hospital & Columbia University Medical Center.
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Journal ArticleDOI
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease.
William J. Sandborn,Brian G. Feagan,Richard N. Fedorak,Ellen Scherl,Mark R. Fleisher,Seymour Katz,Jewel Johanns,Marion Blank,Paul Rutgeerts +8 more
TL;DR: Ustekinumab induced a clinical response in patients with moderate-to-severe Crohn's disease, especially in patients previously given infliximab.
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Culture Independent Analysis of Ileal Mucosa Reveals a Selective Increase in Invasive Escherichia Coli of Novel Phylogeny Relative to Depletion of Clostridiales in Crohn's Disease Involving the Ileum
Martin Baumgart,Belgin Dogan,Mark Rishniw,Gil Weitzman,Brian P. Bosworth,Rhonda K. Yantiss,Renato H. Orsi,Martin Wiedmann,Patrick L. McDonough,Sung Guk Kim,Douglas E. Berg,Ynte H. Schukken,Ellen Scherl,Kenneth W. Simpson +13 more
TL;DR: It is established that dysbiosis of the ileal mucosa-associated flora correlates with an ILEal Crohn's disease (ICD) phenotype, and the possibility that a selective increase in a novel group of invasive E. coli is involved in the etiopathogenesis to Crohn’s disease involving the ilesum is raised.
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CX3CR1+ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22
Randy S. Longman,Randy S. Longman,Gretchen E. Diehl,Daniel A. Victorio,Daniel A. Victorio,Jun R. Huh,Carolina Galan,Emily R. Miraldi,Arun Swaminath,Richard Bonneau,Ellen Scherl,Ellen Scherl,Dan R. Littman +12 more
TL;DR: Intestinal CX3CR1+ mononuclear phagocytes regulate ILC3 in vivo in response to colitis associated microbial signals.
Journal ArticleDOI
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Lasha Gogokhia,Lasha Gogokhia,Kate Buhrke,Rickesha Bell,Brenden Hoffman,D. Garrett Brown,Christin Hanke-Gogokhia,Nadim J. Ajami,Matthew C. Wong,Arevik Ghazaryan,John F. Valentine,Nathan T. Porter,Eric C. Martens,Ryan M. O'Connell,Vinita Jacob,Ellen Scherl,Carl V. Crawford,W. Zac Stephens,Sherwood R. Casjens,Randy S. Longman,June L. Round +20 more
TL;DR: Results indicate that bacteriophages can alter mucosal immunity to impact mammalian health and reduce phages compared to non-responders.
colitis-associated innate lymphoid cell production of IL-22
Randy S. Longman,Gretchen E. Diehl,Daniel A. Victorio,Jun R. Huh,Carolina Galan,Emily R. Miraldi,Arun Swaminath,Richard Bonneau,Ellen Scherl,Dan R. Littman +9 more
TL;DR: In this paper, CX3CR1+ mononuclear phagocytes regulate ILC3 in vivo in response to colitis associated microbial signals, and the results showed that the phagocyte activity was positively correlated with colitis-associated microbial signals.