J
J. Bruce German
Researcher at University of California, Davis
Publications - 327
Citations - 26633
J. Bruce German is an academic researcher from University of California, Davis. The author has contributed to research in topics: Fatty acid & Lactation. The author has an hindex of 83, co-authored 321 publications receiving 23370 citations. Previous affiliations of J. Bruce German include Nestlé & University of California.
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Journal ArticleDOI
Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants.
Steven A. Frese,Andra Hutton,Lindsey Contreras,Claire Shaw,Michelle C. Palumbo,Giorgio Casaburi,Gege Xu,Jasmine C.C. Davis,Carlito B. Lebrilla,Bethany M. Henrick,Samara L. Freeman,Daniela Barile,J. Bruce German,David A. Mills,Jennifer T. Smilowitz,Mark A. Underwood,Mark A. Underwood +16 more
TL;DR: Brefed infants could be stably colonized at high levels by provision of B. infantis EVC001, with significant changes to the overall microbiome composition persisting more than a month later, whether the infants were born vaginally or by caesarean section.
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Glycosylation of Human Milk Lactoferrin Exhibits Dynamic Changes During Early Lactation Enhancing Its Role in Pathogenic Bacteria-Host Interactions
Mariana Barboza,Janneth Pinzon,Saumiya Wickramasinghe,John W. Froehlich,Isabelle Moeller,Jennifer T. Smilowitz,L. Renee Ruhaak,Jincui Huang,Bo Lönnerdal,J. Bruce German,Juan F. Medrano,Bart C. Weimer,Carlito B. Lebrilla +12 more
TL;DR: It was found that fucosyltransferase expression increased during entire period, whereas expression of genes for the oligosaccharyl transferase complex decreased in the second week, and that glyco-variation is involved in modulating pathogen association.
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Liposomes as agents of DNA transfer.
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Extensive in vivo Human Milk Peptidomics Reveals Specific Proteolysis Yielding Protective Antimicrobial Peptides
David C. Dallas,Andres Guerrero,Nora Khaldi,Patricia A. Castillo,William F. Martin,Jennifer T. Smilowitz,Charles L. Bevins,Daniela Barile,J. Bruce German,Carlito B. Lebrilla +9 more
TL;DR: The predigestion of milk proteins and the consequent release of antibacterial peptides may provide a selective advantage through evolution by protecting both the mother's mammary gland and her nursing offspring from infection.
Journal ArticleDOI
A novel gene cluster allows preferential utilization of fucosylated milk oligosaccharides in Bifidobacterium longum subsp. longum SC596
Daniel Garrido,Daniel Garrido,Santiago Ruiz-Moyano,Nina Kirmiz,Jasmine C.C. Davis,Sarah M. Totten,Danielle G. Lemay,Juan A. Ugalde,J. Bruce German,Carlito B. Lebrilla,David A. Mills +10 more
TL;DR: This work clarifies the genomic and physiological variation of infant-borne B. longum to HMO consumption, which resembles B. infantis and suggests the capability to preferentially consume fucosylated HMO suggests a competitive advantage for these unique B.Longum strains in the breast-fed infant gut.