J
J. Bruce German
Researcher at University of California, Davis
Publications - 327
Citations - 26633
J. Bruce German is an academic researcher from University of California, Davis. The author has contributed to research in topics: Fatty acid & Lactation. The author has an hindex of 83, co-authored 321 publications receiving 23370 citations. Previous affiliations of J. Bruce German include Nestlé & University of California.
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Journal ArticleDOI
Dietary Considerations in Autism Spectrum Disorders: The Potential Role of Protein Digestion and Microbial Putrefaction in the Gut-Brain Axis
Megan R. Sanctuary,Jennifer N. Kain,Kathleen Angkustsiri,Kathleen Angkustsiri,J. Bruce German +4 more
TL;DR: These findings support the hypothesis that entry of dietary peptides from the gut lumen into the vasculature are associated with an aberrant immune response and support the idea that the fragile gut of some children with ASD is at risk for GI symptoms that may be amenable to improvement with specific dietary changes.
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Analytical metabolomics: Nutritional opportunities for personalized health
TL;DR: These fields will eventually blend together through development of new technologies in metabolomics and genomics into a new area of clinical chemistry: personalized medicine.
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N-Linked Glycan Profiling of Mature Human Milk by High-Performance Microfluidic Chip Liquid Chromatography Time-of-Flight Tandem Mass Spectrometry
David C. Dallas,William F. Martin,John S. Strum,Angela M. Zivkovic,Jennifer T. Smilowitz,Mark A. Underwood,Michael Affolter,Carlito B. Lebrilla,J. Bruce German +8 more
TL;DR: Fifty-two N-linked glycan compositions were identified, and 24 were confirmed via tandem mass spectra analysis, and the majority (70%) of total N-glycan abundance was composed of N- glycans found in all three milk samples.
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Nutritional Lipidomics: Molecular Metabolism, Analytics, and Diagnostics
Jennifer T. Smilowitz,Angela M. Zivkovic,Yu-Jui Yvonne Wan,Steve M Watkins,Malin L. Nording,Bruce D. Hammock,J. Bruce German +6 more
TL;DR: The field of lipidomics is providing nutritional science a more comprehensive view of lipid intermediates, and the strategy of combining tandem analytical methods to perform the sensitive, high-throughput, quantitative, and comprehensive analysis of lipid metabolites of very large numbers of molecules is poised to drive the field forward rapidly.
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Predicting the Important Enzymes in Human Breast Milk Digestion
Nora Khaldi,Vaishnavi Vijayakumar,David C. Dallas,Andres Guerrero,Saumya Wickramasinghe,Jennifer T. Smilowitz,Juan F. Medrano,Carlito B. Lebrilla,Denis C. Shields,J. Bruce German +9 more
TL;DR: The results indicate that several enzymes are actively taking part in the digestion of human milk proteins within the mammary gland, including plasmin and/or trypsin, elastase, cathepsin D, pepsin, chymotrypsin and a glutamyl endopeptidase-like enzyme.