J. Bruce German

TL;DR: This lipidomic based phenotyping approach demonstrated that individual responsiveness to ω3 fatty acids is highly variable and measurable, and could be used as a means to assess the effectiveness of ω2 interventions in modifying disease risk and determining metabolic phenotype.

TL;DR: Plasma total oxylipins as well as several hydroxyoctadecadienoic acids, hydroxyeicosatetraenoic acid, and leukotriene B4 metabolites were among the metabolites that were significantly lower than in patients whose proteinuria either did not improve or worsened, suggesting responsiveness to ω-3 fatty acid supplementation in IgAN patients.

TL;DR: Variations in expression or glycosylation levels are demonstrated for several other abundant whey proteins, including tenascin, bile salt-stimulated lipase, xanthine dehydrogenase, and mannose receptor.

TL;DR: In order to better understand protein digestion in preterm and term infants, future studies should examine protein and peptide fragment products of digestion in saliva, gastric, intestinal and fecal samples, as well as the effects of the gut micro biome on protein degradation.

TL;DR: The quantitation method was applied to 20 human milk samples to determine the variations in HMO concentrations from women classified as secretors and nonsecretors, a phenotype that can be identified by the concentration of 2′-fucosylation in their milk.