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J. Christian Bode

Researcher at Bosch

Publications -  26
Citations -  1565

J. Christian Bode is an academic researcher from Bosch. The author has contributed to research in topics: Alcoholic liver disease & Liver disease. The author has an hindex of 13, co-authored 24 publications receiving 1459 citations. Previous affiliations of J. Christian Bode include University of Hohenheim.

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Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease

TL;DR: The results of this study indicate that alcohol abuse impairs the function of the intestinal barrier, which might enhance the translocation of bacterial toxins, thereby contributing to inflammatory processes in alcoholic liver disease.
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Concentrations of lipopolysaccharide-binding protein, bactericidal/permeability-increasing protein, soluble CD14 and plasma lipids in relation to endotoxaemia in patients with alcoholic liver disease.

TL;DR: Endotoxin antagonists, such as bactericidal/permeability-increasing protein and high-density lipoprotein, were increased in the pre-cirrhotic stages, whereas a significant reduction of the latter was observed in cirrhosis, and endotoxin and the concentration of binding factors that are involved in the action of endotoxin on its target cells were increased.
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Models of alcoholic liver disease in rodents: a critical evaluation.

TL;DR: This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan, where Christiane Bode, Alexandr Parlesak, and J. Christian Bode presented the course of the pathological spectrum of alcoholic liver disease in humans.
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Prevalence of small bowel bacterial overgrowth and its association with nutrition intake in nonhospitalized older adults.

TL;DR: To determine the prevalence of small bowel bacterial overgrowth in older adults and to assess whether SBBO is associated with abdominal complaints and nutrient intake, a large number of older adults are surveyed.