J
J. Van Damme
Researcher at Katholieke Universiteit Leuven
Publications - 124
Citations - 10055
J. Van Damme is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Chemokine & Cytokine. The author has an hindex of 54, co-authored 124 publications receiving 9814 citations. Previous affiliations of J. Van Damme include National Institutes of Health & Catholic University of Leuven.
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Journal ArticleDOI
Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.
J. Van Damme,Ghislain Opdenakker,Richard J. Simpson,Michael R. Rubira,S Cayphas,Anne Vink,Alfons Billiau,J Van Snick +7 more
TL;DR: A factor that promotes the growth of certain B cell hybridomas and of plasmacytomas is shown to be produced by normal human fibroblasts and by a line of human osteosarcoma cells after treatment with IL-1 or TNF.
Journal Article
Il-1 stimulates il-6 production in endothelial cells
Marina Sironi,F. Breviario,P. Proserpio,Andrea Biondi,Annunciata Vecchi,J. Van Damme,Elisabetta Dejana,A. Mantovani +7 more
TL;DR: The capacity to produce IL-6 may represent an important mechanism by which endothelial cells participate in inflammatory and immune reactions, and is defined as a communication signal between vascular and immunocompetent cells.
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Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes.
Dennis D. Taub,Paul Proost,William J. Murphy,Miriam R. Anver,Dan L. Longo,J. Van Damme,Joost J. Oppenheim +6 more
TL;DR: It is reported here that natural MCP-1 as well as synthetic preparations of M CP-2 and MCP3 stimulate significant in vitro chemotaxis of human peripheral blood T lymphocytes and may play an important role in immune cell recruitment into sites of antigenic challenge.
Journal Article
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.
Silvano Sozzani,Federica Sallusto,Walter Luini,Dan Zhou,Lorenzo Piemonti,Paola Allavena,J. Van Damme,Salvatore Valitutti,Antonio Lanzavecchia,Alberto Mantovani +9 more
TL;DR: FMLP, C5a, and the C-C chemokines monocyte chemotactic protein (MCP)-3, MIP-1 alpha/LD78, and RANTES elicited chemotact migration and a rise of intracellular free calcium in dendritic cells, and Chemoattractants were inactive as chemoattractant.
Journal ArticleDOI
A Potent Antimicrobial Protein from Onion Seeds Showing Sequence Homology to Plant Lipid Transfer Proteins
Bruno P. A. Cammue,Karin Thevissen,M. Hendriks,Kristel Eggermont,Inge J.W.M. Goderis,Paul Proost,J. Van Damme,Rupert W. Osborn,F. Guerbette,J.-C. Kader,Willem F. Broekaert +10 more
TL;DR: An antimicrobial protein of about 10 kD, called Ace-AMP1, was isolated from onion (Allium cepa L.) seeds and was unable to transfer phospholipids from liposomes to mitochondria, whereas lipid transfer proteins from wheat and maize seeds showed little or no antimicrobial activity, whereas the radish lipid transfer protein displayed antifungal activity only in media with low cation concentrations.