J
Jan-Niklas Runge
Researcher at University of Zurich
Publications - 8
Citations - 90
Jan-Niklas Runge is an academic researcher from University of Zurich. The author has contributed to research in topics: House mice & Gene drive. The author has an hindex of 3, co-authored 6 publications receiving 49 citations.
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Journal ArticleDOI
Resistance to natural and synthetic gene drive systems.
Tom A. R. Price,Nikolai Windbichler,Robert L. Unckless,Andreas Sutter,Jan-Niklas Runge,Perran A. Ross,Andrew Pomiankowski,Nicole L. Nuckolls,Catherine Montchamp-Moreau,Nicole Mideo,Oliver Martin,Andri Manser,Mathieu Legros,Amanda M. Larracuente,Luke Holman,John Godwin,Neil J. Gemmell,Cécile Courret,Cécile Courret,Anna Buchman,Luke G. Barrett,Anna K. Lindholm +21 more
TL;DR: This review summarizes the current knowledge of drive resistance in both natural and synthetic gene drives and explores how insights from naturally occurring and synthetic drive systems can be integrated to improve the design of gene drives, better predict the outcome of releases and understand genomic conflict in general.
Journal ArticleDOI
Carrying a selfish genetic element predicts increased migration propensity in free-living wild house mice
TL;DR: It is shown that juvenile mice carrying the t haplotype were more likely to emigrate from and were more often found as migrants within a long-term free-living house mouse population, suggesting variations of the t that manipulate migration propensity could increase in fitness in a meta-population.
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Steroid hormones in hair reveal sexual maturity and competition in wild house mice (Mus musculus domesticus).
Esther H.D. Carlitz,Jan-Niklas Runge,Barbara König,Lennart Winkler,Clemens Kirschbaum,Wei Gao,Anna K. Lindholm +6 more
TL;DR: It is shown that body weight, sex and age significantly predict cumulative testosterone and progesterone levels, allowing the differentiation between subadults and adults in both sexes and highlighting the biological validity of hair steroid measurements.
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One Third of Patients before Endoprosthesis Implantation Show an Oral Focus as Potential Source of Infectious Complication—The Value of Pre-Operative Dental Risk Stratification in a German Cohort
Gerhard Schmalz,Florentine Reuschel,Markus Bartl,Laura Schmidt,Jan-Niklas Runge,Rainer Haak,Szymon Goralski,Andreas Roth,Dirk Ziebolz +8 more
TL;DR: German patients before EP have a high periodontal treatment need and show frequently a potential oral focus of infection, underlining the necessity of including dental examination and risk stratification as part of the pre-operative assessment prior to EP implantation.
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Experiments confirm a dispersive phenotype associated with a natural gene drive system.
TL;DR: Meiotic drivers are genetic entities that increase their own probability of being transmitted to offspring, usually to the detriment of the rest of the organism as discussed by the authors, thus "selfishly" increasing their f...