J
Jason E. Gestwicki
Researcher at University of California, San Francisco
Publications - 280
Citations - 27231
Jason E. Gestwicki is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Chaperone (protein) & Heat shock protein. The author has an hindex of 69, co-authored 250 publications receiving 23446 citations. Previous affiliations of Jason E. Gestwicki include Research Triangle Park & Stanford University.
Papers
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Journal ArticleDOI
Small molecule tools for molecular recognition of tau fibril conformations.
TL;DR: In this paper , a library of polyanionic inducers of tau aggregation is developed to create conformationally diverse tau fibril forms in vitro and in seeded cell culture.
Proceedings ArticleDOI
Comparison of thermal and microwave energy: model biological systems and energy input
TL;DR: In this paper, a microwave reactor system that allows comparison of thermal and microwave-catalyzed reactions under conditions amenable to biological systems has been developed, and it has been shown that the rate enhancements provided by microwave irradiation are thermal in origin.
Journal ArticleDOI
Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models
Pengfei Xu,Joy C. Yang,Shuangli Ning,Bo Chen,Christopher Nip,Qiang Wei,Liangren Liu,Oleta T. Johnson,Allen C. Gao,Jason E. Gestwicki,Christopher H. Evans,Chengfei Liu +11 more
TL;DR: In this article , the heat shock protein 70/STIP1 homology and U-box-containing protein 1 (HSP70/STUB1) machinery are involved in androgen receptor (AR) and AR variant protein stabilization.