J
Jayashri Viswanathan
Researcher at University of California, Davis
Publications - 2
Citations - 170
Jayashri Viswanathan is an academic researcher from University of California, Davis. The author has contributed to research in topics: Ibogaine & Pharmacophore. The author has an hindex of 2, co-authored 2 publications receiving 52 citations.
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Journal ArticleDOI
A non-hallucinogenic psychedelic analogue with therapeutic potential
Lindsay P. Cameron,Robert J. Tombari,Ju Lu,Alexander J. Pell,Zefan Q. Hurley,Yann Ehinger,Maxemiliano V. Vargas,Matthew N. McCarroll,Jack C. Taylor,Douglas Myers-Turnbull,Taohui Liu,Bianca Yaghoobi,Lauren J. Laskowski,Emilie I. Anderson,Guoliang Zhang,Jayashri Viswanathan,Brandon M. Brown,Michelle Tjia,Lee E. Dunlap,Zachary Rabow,Oliver Fiehn,Heike Wulff,John D. McCorvy,Pamela J. Lein,David Kokel,Dorit Ron,Jamie Peters,Yi Zuo,David E. Olson +28 more
TL;DR: This work demonstrates that, through careful chemical design, it is possible to modify a psychedelic compound to produce a safer, non-hallucinogenic variant that has therapeutic potential.
Journal ArticleDOI
Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.
Lee E. Dunlap,Arya Azinfar,Calvin Ly,Lindsay P. Cameron,Jayashri Viswanathan,Robert J. Tombari,Douglas Myers-Turnbull,Jack C. Taylor,Ana Cristina Grodzki,Pamela J. Lein,David Kokel,David E. Olson +11 more
TL;DR: This work has discovered several key features of the psychoplastogenic pharmacophore and used this information to develop N,N-dimethylaminoisotryptamine (isoDMT) Psychoplastogens that are easier to synthesize, have improved physicochemical properties, and possess reduced hallucinogenic potential as compared to their DMT counterparts.