E
Emilie I. Anderson
Researcher at Medical College of Wisconsin
Publications - 3
Citations - 177
Emilie I. Anderson is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Hallucinogen & G protein-coupled receptor. The author has an hindex of 2, co-authored 2 publications receiving 40 citations.
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Journal ArticleDOI
A non-hallucinogenic psychedelic analogue with therapeutic potential
Lindsay P. Cameron,Robert J. Tombari,Ju Lu,Alexander J. Pell,Zefan Q. Hurley,Yann Ehinger,Maxemiliano V. Vargas,Matthew N. McCarroll,Jack C. Taylor,Douglas Myers-Turnbull,Taohui Liu,Bianca Yaghoobi,Lauren J. Laskowski,Emilie I. Anderson,Guoliang Zhang,Jayashri Viswanathan,Brandon M. Brown,Michelle Tjia,Lee E. Dunlap,Zachary Rabow,Oliver Fiehn,Heike Wulff,John D. McCorvy,Pamela J. Lein,David Kokel,Dorit Ron,Jamie Peters,Yi Zuo,David E. Olson +28 more
TL;DR: This work demonstrates that, through careful chemical design, it is possible to modify a psychedelic compound to produce a safer, non-hallucinogenic variant that has therapeutic potential.
Journal ArticleDOI
Investigation of the structure-activity relationships of psilocybin analogues
Adam K. Klein,Muhammad Chatha,Lauren J. Laskowski,Emilie I. Anderson,Simon D. Brandt,Stephen J. Chapman,John D. McCorvy,Adam L. Halberstadt,Adam L. Halberstadt +8 more
TL;DR: The tryptamine derivatives have psilocybin-like pharmacological properties, supporting their classification as psychedelic drugs.
Journal ArticleDOI
Conformational selection guides β-arrestin recruitment at a biased G protein–coupled receptor
Andrew B. Kleist,Shawn Jenjak,Andrija Sente,Lauren J. Laskowski,Martyna Szpakowska,Maggie M. Calkins,Emilie I. Anderson,Lisa McNally,Raimond Heukers,Vladimir Bobkov,Francis C. Peterson,Monica A. Thomas,Andy Chevigné,Martine J. Smit,John D. McCorvy,M. Madan Babu,Brian F. Volkman +16 more
TL;DR: NMR experiments on 13CH3-ε-methionine-labeled ACKR3 reveal that β-arrestin recruitment is associated with conformational exchange at key regions of the extracellular ligand-binding pocket and intracellular β-Arrestin-coupling region.