Jeff Nie

TL;DR: It is demonstrated that H3K27me3 modifications change during early differentiation, both relieving existing repressive domains and imparting new ones, and that colocalization with H3k4me3 is not restricted to pluripotent cells.

TL;DR: The Quantitative Parallel Aptamer Selection System (QPASS) is devised, which integrates microfluidic selection and next-generation sequencing with in situ-synthesized aptamer arrays, enabling simultaneous measurement of affinity and specificity for thousands of candidate aptamers in parallel.

TL;DR: Deep RNA sequencing of the blastema over a time course in the axolotl found a prominent burst in oncogene expression during the first day and blastemal/limb bud genes peaking at 7 to 14 days, and genes involved in angiogenesis, wound healing, defense/immunity, and bone development are enriched during blastema formation and development.

TL;DR: Surprisingly, the widely used Pearson method is generally less efficient, and so is the Distance Covariance method that can find gene pairs of multiple relationships, while the Weighted Rank methods perform well in identifying coordinated transcription factors that control the same biological processes and traits.

TL;DR: Results indicate that the transcription factor BpERF13 regulates physiological processes underlying cold tolerance in woody plants.