J
Jelena R. Ghadri
Researcher at University of Zurich
Publications - 98
Citations - 4538
Jelena R. Ghadri is an academic researcher from University of Zurich. The author has contributed to research in topics: Coronary artery disease & Myocardial infarction. The author has an hindex of 28, co-authored 89 publications receiving 3515 citations.
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Journal ArticleDOI
Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy
Christian Templin,Jelena R. Ghadri,Johanna Diekmann,L. Christian Napp,Dana Roxana Bataiosu,Milosz Jaguszewski,Victoria L. Cammann,Annahita Sarcon,Verena Geyer,Catharina A. Neumann,Burkhardt Seifert,Jens P. Hellermann,Moritz Schwyzer,Katharina Eisenhardt,Josef Jenewein,Jennifer Franke,Hugo A. Katus,Christof Burgdorf,Heribert Schunkert,Christian Moeller,Holger Thiele,Johann Bauersachs,Carsten Tschöpe,Heinz-Peter Schultheiss,Charles A. Laney,Lawrence Rajan,Guido Michels,Roman Pfister,Christian Ukena,Michael Böhm,Raimund Erbel,Alessandro Cuneo,Karl-Heinz Kuck,Claudius Jacobshagen,Gerd Hasenfuss,M. Karakas,M. Karakas,Wolfgang Koenig,Wolfgang Koenig,Wolfgang Rottbauer,Samir M. Said,Ruediger C. Braun-Dullaeus,Florim Cuculi,Adrian P. Banning,Thomas Fischer,Tuija Vasankari,K.E. Juhani Airaksinen,Marcin Fijałkowski,Andrzej Rynkiewicz,Maciej Pawlak,Grzegorz Opolski,Rafal Dworakowski,Philip MacCarthy,Christoph Kaiser,Stefan Osswald,Leonarda Galiuto,Filippo Crea,Wolfgang Dichtl,Wolfgang-Michael Franz,Klaus Empen,Stephan B. Felix,Clément Delmas,Olivier Lairez,Paul Erne,Jeroen J. Bax,Ian Ford,Frank Ruschitzka,Abhiram Prasad,Thomas F. Lüscher +68 more
TL;DR: Patients with takotsubo cardiomyopathy had a higher prevalence of neurologic or psychiatric disorders than did those with an acute coronary syndrome and physical triggers, acute neurologics or psychiatric diseases, high troponin levels, and a low ejection fraction on admission were independent predictors for in-hospital complications.
Journal ArticleDOI
Diagnostic Value of 13N-Ammonia Myocardial Perfusion PET: Added Value of Myocardial Flow Reserve
Michael Fiechter,Jelena R. Ghadri,Catherine Gebhard,Tobias A. Fuchs,Aju P. Pazhenkottil,Rene Nkoulou,Bernhard A. Herzog,Christophe A. Wyss,Oliver Gaemperli,Philipp A. Kaufmann +9 more
TL;DR: The quantification of MFR in 13N-ammonia PET/CT MPI provides a substantial added diagnostic value for detection of CAD, particularly in patients with normal MPI results, which helps to unmask clinically significant CAD.
Journal ArticleDOI
Vascular lesions induced by renal nerve ablation as assessed by optical coherence tomography: pre- and post-procedural comparison with the Simplicity® catheter system and the EnligHTN™ multi-electrode renal denervation catheter
Christian Templin,Milosz Jaguszewski,Jelena R. Ghadri,Isabella Sudano,Roman Gaehwiler,Jens P. Hellermann,Renate Schoenenberger-Berzins,Ulf Landmesser,Paul Erne,Georg Noll,Thomas F. Lüscher +10 more
TL;DR: It is shown that diffuse renal artery constriction and local tissue damage at the ablation site with oedema and thrombus formation occur after RNA and that OCT visualizes vascular lesions not apparent on angiography, which suggests that dual antiplatelet therapy may be required during RNA.
Journal ArticleDOI
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy.
Thomas Borchert,Daniela Hübscher,Celina Isabell Guessoum,Tuan-Dinh D. Lam,Jelena R. Ghadri,Isabel N. Schellinger,Malte Tiburcy,Norman Y. Liaw,Yun Li,Jan Haas,Samuel Sossalla,Mia Aurelia Huber,Lukas Cyganek,Claudius Jacobshagen,Ralf Dressel,Uwe Raaz,Viacheslav O. Nikolaev,Kaomei Guan,Holger Thiele,Benjamin Meder,Bernd Wollnik,Wolfram-Hubertus Zimmermann,Thomas F. Lüscher,Gerd Hasenfuss,Christian Templin,Katrin Streckfuss-Bömeke +25 more
TL;DR: An in-vitro induced pluripotent stem cell (iPSC) model of Takotsubo syndrome was established to test the hypothesis of altered β-adrenergic signaling in TTS iPSC-cardiomyocytes (CMs), and to explore whether genetic susceptibility underlies the pathogenesis of TTS.
Journal ArticleDOI
Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head to Head Comparison with 13N-Ammonia PET.
Rene Nkoulou,Tobias A. Fuchs,Aju P. Pazhenkottil,Silke M. Küest,Jelena R. Ghadri,Julia Stehli,Michael Fiechter,Bernhard A. Herzog,Oliver Gaemperli,Ronny R. Buechel,Philipp A. Kaufmann +10 more
TL;DR: The estimation of absolute MBF index values by CZT SPECT MPI with 99mTc-tetrofosmin is technically feasible, although hyperemic values are significantly lower than from PET with 13N-ammonia, resulting in a substantial underestimation of MFR.