J
Jennifer L. Shepard
Researcher at Harvard University
Publications - 12
Citations - 3332
Jennifer L. Shepard is an academic researcher from Harvard University. The author has contributed to research in topics: Zebrafish & Genome instability. The author has an hindex of 11, co-authored 12 publications receiving 3179 citations. Previous affiliations of Jennifer L. Shepard include Howard Hughes Medical Institute & Massachusetts Institute of Technology.
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Journal ArticleDOI
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
Adriana Donovan,Alison Brownlie,Alison Brownlie,Yi Zhou,Jennifer L. Shepard,Stephen J. Pratt,John Moynihan,Barry H. Paw,Anna Drejer,Bruce A. Barut,Bruce A. Barut,Agustín G. Zapata,Terence C. Law,Carlo Brugnara,Samuel E. Lux,Geraldine S. Pinkus,Jack L. Pinkus,Paul D. Kingsley,James Palis,Mark D. Fleming,Mark D. Fleming,Nancy C. Andrews,Nancy C. Andrews,Leonard I. Zon,Leonard I. Zon +24 more
TL;DR: The gene responsible for the hypochromic anaemia of the zebrafish mutant weissherbst is identified and Ferroportin1 function may be perturbed in mammalian disorders of iron deficiency or overload.
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Hematopoietic stem cell fate is established by the Notch–Runx pathway
TL;DR: The Notch-Runx pathway is defined as critical for the developmental specification of H SC fate and the subsequent homeostasis of HSC number, thus providing a mechanism for amplifying stem cells in vivo.
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Zebrafish as a cancer model system
TL;DR: The zebrafish, with its combination of forward genetics and vertebrate biology, has great potential as a cancer model system.
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Implantation in Vivo and Retrieval of Artificial Structures Consisting of Rabbit and Human Urothelium and Human Bladder Muscle
TL;DR: Feelings of feasibility of using polyglycolic acid polymers as substrates for the creation of human urothelial and muscle grafts for genitourinary reconstruction are suggested.
Journal ArticleDOI
Small molecules that delay S phase suppress a zebrafish bmyb mutant.
Howard M. Stern,Ryan D. Murphey,Jennifer L. Shepard,James F. Amatruda,Christian T. Straub,Kathleen L. Pfaff,Gerhard J. Weber,John A. Tallarico,Randall W. King,Leonard I. Zon +9 more
TL;DR: This study demonstrates that chemical suppressor screening in zebrafish can identify compounds with cell-cycle activity and can be used to identify pathways that interact with specific cell- cycle phenotypes.