J
Jian Mei
Researcher at Centers for Disease Control and Prevention
Publications - 44
Citations - 2921
Jian Mei is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 27, co-authored 44 publications receiving 2585 citations. Previous affiliations of Jian Mei include Chinese Center for Disease Control and Prevention.
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Journal ArticleDOI
Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans
Iñaki Comas,Mireia Coscolla,Mireia Coscolla,Tao Luo,Sonia Borrell,Sonia Borrell,Kathryn E. Holt,Midori Kato-Maeda,Julian Parkhill,Bijaya Malla,Bijaya Malla,Stefan Berg,Guy E. Thwaites,Dorothy Yeboah-Manu,Graham H. Bothamley,Jian Mei,Lan-Hai Wei,Stephen D. Bentley,Simon R. Harris,Stefan Niemann,Roland Diel,Abraham Aseffa,Qian Gao,Douglas B. Young,Douglas B. Young,Sebastien Gagneux,Sebastien Gagneux +26 more
TL;DR: Coalescent analyses indicate that MTBC emerged about 70,000 years ago, accompanied migrations of anatomically modern humans out of Africa and expanded as a consequence of increases in human population density during the Neolithic period, consistent with MTBC displaying characteristics indicative of adaptation to both low and high host densities.
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Transmission of multidrug-resistant Mycobacterium tuberculosis in Shanghai, China: a retrospective observational study using whole-genome sequencing and epidemiological investigation
Chongguang Yang,Chongguang Yang,Tao Luo,Tao Luo,Xin Shen,Jie Wu,Mingyu Gan,Peng Xu,Zheyuan Wu,Senlin Lin,Jiyun Tian,Qingyun Liu,Zheng An Yuan,Jian Mei,Kathryn DeRiemer,Qian Gao +15 more
TL;DR: Recent transmission of MDR tuberculosis strains, with increasing drug-resistance, drives the M DR tuberculosis epidemic in Shanghai, China.
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Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients
Gang Sun,Tao Luo,Chongguang Yang,Xinran Dong,Jing Li,Yongqiang Zhu,Huajun Zheng,Weidong Tian,Shengyue Wang,Clifton E. Barry,Jian Mei,Qian Gao +11 more
TL;DR: The M. tuberculosis population within patients exhibited considerable genetic diversity, which underwent selections for most fit resistant mutant, and the need for early diagnosis of tuberculosis to decrease the chance of evolving highly fit drug-resistant strains is emphasized.
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Cross-Priming Amplification for Rapid Detection of Mycobacterium tuberculosis in Sputum Specimens
Rendong Fang,Xia Li,Lin Hu,Qimin You,Jing Li,Jie Wu,Peng Xu,Peng Xu,Huayan Zhong,Ying Luo,Jian Mei,Qian Gao +11 more
TL;DR: Cross-priming amplification technology for tuberculosis diagnosis from sputum specimens was evaluated and the specificity of CPA in culture-negative specimens was 98.8%.
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Southern East Asian origin and coexpansion of Mycobacterium tuberculosis Beijing family with Han Chinese
Tao Luo,Iñaki Comas,Dan Luo,Bing Lu,Jie Wu,Lan-Hai Wei,Chongguang Yang,Qingyun Liu,Mingyu Gan,Gang Sun,Xin Shen,Feiying Liu,Sebastien Gagneux,Jian Mei,Rushu Lan,Kanglin Wan,Qian Gao +16 more
TL;DR: Wang et al. as discussed by the authors characterized the global diversity of the Beijing family based on whole-genome sequences of 358 Beijing strains and showed that the Beijing strains endemic in East Asia are genetically diverse, whereas the globally emerging strains mostly belong to a more homogenous subtype known as "modern" Beijing sublineage.