J
Jianyi Zhang
Researcher at University of Alabama at Birmingham
Publications - 256
Citations - 10608
Jianyi Zhang is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Stem cell & Induced pluripotent stem cell. The author has an hindex of 54, co-authored 243 publications receiving 8618 citations. Previous affiliations of Jianyi Zhang include Tengion & University of Florida College of Public Health and Health Professions.
Papers
More filters
Journal ArticleDOI
Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells
Lei Ye,Ying Hua Chang,Qiang Xiong,Pengyuan Zhang,Liying Zhang,Porur E. Somasundaram,Mike Lepley,Cory Swingen,Liping Su,Jacqueline S. Wendel,Jing Guo,Albert Jang,Daniel Rosenbush,Lucas Greder,James R. Dutton,Jianhua Zhang,Timothy J. Kamp,Dan S. Kaufman,Ying Ge,Jianyi Zhang +19 more
TL;DR: A porcine model of acute myocardial infarction is utilized to investigate the functional impact of intramyocardial transplantation of hiPSC-derived cardiomyocytes, endothelial cells, and smooth muscle cells, in combination with a 3D fibrin patch loaded with insulin growth factor (IGF)-encapsulated microspheres.
Journal ArticleDOI
Contrast-enhanced first pass myocardial perfusion imaging: Correlation between myocardial blood flow in dogs at rest and during hyperemia
N. Wilke,C. Simm,C. Simm,Jianyi Zhang,Jutta M. Ellermann,X. Ya,Hellmut Merkle,G. Path,H. Lüdemann,H. Lüdemann,Robert J. Bache,Kamil Ugurbil +11 more
TL;DR: The results suggest that with intracardiac injections of exogenous contrast agent, myocardial perfusion can be assessed parametrically with first pass contrast enhanced ultrafast MRI.
Journal ArticleDOI
Large Cardiac Muscle Patches Engineered From Human Induced-Pluripotent Stem Cell-Derived Cardiac Cells Improve Recovery From Myocardial Infarction in Swine.
Ling Gao,Zachery R. Gregorich,Wuqiang Zhu,Saidulu Mattapally,Yasin Oduk,Xi Lou,Ramaswamy Kannappan,Anton V. Borovjagin,Gregory P. Walcott,Andrew E. Pollard,Vladimir G. Fast,Xinyang Hu,Steven G. Lloyd,Ying Ge,Jianyi Zhang +14 more
TL;DR: The hCMP transplantation was associated with significant improvements in left ventricular function, infarct size,Myocardial wall stress, myocardial hypertrophy, and reduced apoptosis in the periscar boarder zone myocardium.
Journal ArticleDOI
The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart
Jennifer Q. Kwong,Xiyuan Lu,Robert N. Correll,Jennifer A. Schwanekamp,Ronald J. Vagnozzi,Michelle A. Sargent,Allen J. York,Jianyi Zhang,Donald M. Bers,Jeffery D. Molkentin +9 more
TL;DR: MCU is a dedicated regulator of short-term mitochondrial Ca(2+) loading underlying a "fight-or-flight" response that acutely matches cardiac workload with ATP production in mice generated with adult and cardiomyocyte-specific deletion of Mcu.
Journal ArticleDOI
Bioenergetic and functional consequences of bone marrow-derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling.
Lepeng Zeng,Qingsong Hu,Xiaohong Wang,Abdul Mansoor,Joseph Lee,Julia Feygin,Ge Zhang,Piradeep Suntharalingam,Sherry Boozer,Abner M. Mhashilkar,Carmelo J. Panetta,Cory Swingen,Robert J. Deans,Arthur H. L. From,Robert J. Bache,Catherine M. Verfaillie,Jianyi Zhang +16 more
TL;DR: Allogeneic pMultistem improved BZ energetics, regional contractile performance, and global left ventricular ejection fraction and may have resulted from paracrine effects that include increased vascular density in the BZ and spared myocytes in the infarct zone.