J
Jingqi Chen
Researcher at Sun Yat-sen University
Publications - 14
Citations - 1965
Jingqi Chen is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Metastasis & Breast cancer. The author has an hindex of 6, co-authored 8 publications receiving 1631 citations. Previous affiliations of Jingqi Chen include Guangzhou Medical University.
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Journal ArticleDOI
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells.
Mei Yang,Mei Yang,Jingqi Chen,Fang Su,Bin Yu,Fengxi Su,Ling Lin,Ling Lin,Yujie Liu,Jian-Dong Huang,Erwei Song +10 more
TL;DR: Macrophages regulate the invasiveness of breast cancer cells through exosome-mediated delivery of oncogenic miRNAs, which provides insight into the mechanisms underlying the metastasis-promoting interactions between macrophages and Breast cancer cells.
Journal ArticleDOI
A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis
Shicheng Su,Qiang Liu,Jingqi Chen,Jianing Chen,Fei Chen,Chonghua He,Di Huang,Wei Wu,Ling Lin,Wei Huang,Jin Zhang,Xiuying Cui,Fang Zheng,Haiyan Li,Herui Yao,Fengxi Su,Erwei Song +16 more
TL;DR: It is shown that mesenchymal-like breast cancer cells activate macrophages to a TAM-like phenotype by GM-CSF, which suggests that a positive feedback loop between GM- CSF and CCL18 is important in breast cancer metastasis.
Journal ArticleDOI
CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3
Jingqi Chen,Jingqi Chen,Yandan Yao,Chang Gong,Fengyan Yu,Shicheng Su,Jianing Chen,Bodu Liu,Hui Deng,Fengsong Wang,Ling Lin,Herui Yao,Fengxi Su,Karen S. Anderson,Qiang Liu,Qiang Liu,Mark E. Ewen,Xuebiao Yao,Erwei Song +18 more
TL;DR: In this article, the authors show that breast TAMs abundantly produce CCL18, and its expression in blood or cancer stroma is associated with metastasis and reduced patient survival.
Journal ArticleDOI
CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer
Ling Lin,Yong-Song Chen,Yandan Yao,Jingqi Chen,Jianing Chen,Songyin Huang,Yunjie Zeng,Herui Yao,Si-Hai Zeng,Yong-Shui Fu,Erwei Song +10 more
TL;DR: It is suggested that CCL18 released from TAMs promotes angiogenesis and tumor progression in breast cancer; thus, CCL 18 may serve as a novel target for anti-angiogenic therapies.
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Markers of Tumor-Initiating Cells Predict Chemoresistance in Breast Cancer
TL;DR: The data suggest that the proportion of BT-ICs is associated with chemotherapeutic resistance of breast cancer, and highlights the importance of targeting T- ICs, rather than eliminating the bulk of rapidly dividing and terminally differentiated cells, in novel anti-cancer strategies.