T
Tanya Yatsunenko
Researcher at Washington University in St. Louis
Publications - 13
Citations - 46554
Tanya Yatsunenko is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Gut flora & Microbiome. The author has an hindex of 11, co-authored 13 publications receiving 39171 citations.
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Journal ArticleDOI
QIIME allows analysis of high-throughput community sequencing data.
J. Gregory Caporaso,Justin Kuczynski,Jesse Stombaugh,Kyle Bittinger,Frederic D. Bushman,Elizabeth K. Costello,Noah Fierer,Antonio Gonzalez Peña,Julia K. Goodrich,Jeffrey I. Gordon,Gavin A. Huttley,Scott T. Kelley,Dan Knights,Jeremy E. Koenig,Ruth E. Ley,Catherine A. Lozupone,Daniel McDonald,Brian D. Muegge,Meg Pirrung,Jens Reeder,Joel Sevinsky,Peter J. Turnbaugh,William A. Walters,Jeremy Widmann,Tanya Yatsunenko,Jesse R. Zaneveld,Rob Knight,Rob Knight +27 more
TL;DR: An overview of the analysis pipeline and links to raw data and processed output from the runs with and without denoising are provided.
Journal ArticleDOI
A core gut microbiome in obese and lean twins
Peter J. Turnbaugh,Micah Hamady,Tanya Yatsunenko,Brandi L. Cantarel,Alexis E. Duncan,Ruth E. Ley,Mitchell L. Sogin,William J. Jones,Bruce A. Roe,Jason P. Affourtit,Michael Egholm,Bernard Henrissat,Andrew C. Heath,Rob Knight,Jeffrey I. Gordon +14 more
TL;DR: The faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers are characterized to address how host genotype, environmental exposure and host adiposity influence the gut microbiome.
Journal ArticleDOI
Human gut microbiome viewed across age and geography
Tanya Yatsunenko,Federico E. Rey,Mark J. Manary,Mark J. Manary,Indi Trehan,Indi Trehan,Maria Gloria Dominguez-Bello,Monica Contreras,Magda Magris,Glida Hidalgo,Robert N. Baldassano,Andrey P. Anokhin,Andrew C. Heath,Barbara B. Warner,Jens Reeder,Justin Kuczynski,J. Gregory Caporaso,Catherine A. Lozupone,Christian L. Lauber,Jose C. Clemente,Dan Knights,Rob Knight,Jeffrey I. Gordon +22 more
TL;DR: The need to consider the microbiome when evaluating human development, nutritional needs, physiological variations and the impact of westernization is underscored, as distinctive features of the functional maturation of the gut microbiome are evident in early infancy as well as adulthood.
Journal ArticleDOI
Gut microbiomes of Malawian twin pairs discordant for kwashiorkor
Michelle I. Smith,Tanya Yatsunenko,Mark J. Manary,Mark J. Manary,Mark J. Manary,Indi Trehan,Indi Trehan,Rajhab S. Mkakosya,Jiye Cheng,Andrew L. Kau,Stephen S. Rich,Patrick Concannon,Josyf C. Mychaleckyj,Jie Liu,Eric R. Houpt,Jia V. Li,Elaine Holmes,Jeremy K. Nicholson,Dan Knights,Luke K. Ursell,Rob Knight,Jeffrey I. Gordon +21 more
TL;DR: The authors investigated the role of the gut microbiome in kwashiorkor, an enigmatic form of severe acute malnutrition that is the consequence of inadequate nutrient intake plus additional environmental insults, and found that RUTF produced a transient maturation of metabolic functions that regressed when administration of RUTF was stopped.
Journal ArticleDOI
Persistent gut microbiota immaturity in malnourished Bangladeshi children
Sathish Subramanian,Sayeeda Huq,Tanya Yatsunenko,Rashidul Haque,Mustafa Mahfuz,Mohammed Ashraful Alam,Amber Benezra,Amber Benezra,Joseph DeStefano,Martin Meier,Brian D. Muegge,Michael J. Barratt,Laura G. VanArendonk,Qunyuan Zhang,Michael A. Province,William A. Petri,Tahmeed Ahmed,Jeffrey I. Gordon +17 more
TL;DR: The results indicate that SAM is associated with significant relative microbiota immaturity that is only partially ameliorated following two widely used nutritional interventions.