J
Jochen Hess
Researcher at German Cancer Research Center
Publications - 125
Citations - 6990
Jochen Hess is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cancer. The author has an hindex of 39, co-authored 110 publications receiving 6071 citations. Previous affiliations of Jochen Hess include University of Würzburg & Heidelberg University.
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Book ChapterDOI
Predictive Factors for Outcome and Quality of Life in HPV-Positive and HPV-Negative HNSCC
TL;DR: The current knowledge on HPV-related alterations in DNA methylation, histone modification, and chromosome remodeling will be summarized and assessment of cancer-related profiles will be discussed as a valuable tool to gain important diagnostic or prognostic information for therapeutic decision-making and clinical management of HNSCC patients.
Journal ArticleDOI
Early activation and induction of apoptosis in T cells is independent of c-Fos.
Hanna Bierbaum,Sven Baumann,Ingrid Herr,Jan Tuckermann,Jochen Hess,Marina Schorpp-Kistner,Peter Angel +6 more
TL;DR: Clear evidence is provided that c‐Fos is not required for apoptosis regulation in activated T cells as well as in thymocytes.
Journal ArticleDOI
Chronic liver inflammation and hepatocellular carcinogenesis are independent of S100A9.
Aurora De Ponti,Lars Wiechert,Ana Stojanovic,Thomas Longerich,Silke Marhenke,Nancy Hogg,Arndt Vogel,Adelheid Cerwenka,Peter Schirmacher,Jochen Hess,Jochen Hess,Peter Angel +11 more
TL;DR: It is demonstrated that, although highly upregulated, calprotectin is dispensable in the onset and development of HCC, and in the maintenance of liver inflammation, which is not affected upon S100a9 deletion.
Journal ArticleDOI
Regulation of submaxillary gland androgen-regulated protein 3A via estrogen receptor 2 in radioresistant head and neck squamous cell carcinoma cells
Jennifer Grünow,Jennifer Grünow,Chao Rong,Jan Hischmann,Karim Zaoui,Christa Flechtenmacher,Klaus-Josef Weber,Peter Plinkert,Jochen Hess,Jochen Hess +9 more
TL;DR: Findings provide compelling experimental evidence that HNSCC with SMR3A and ESR2 co-expression have a higher risk for treatment failure and these patients might benefit from clinically well-established drugs targeting estrogen receptor signaling.
Journal ArticleDOI
Submaxillary gland androgen-regulated protein 3A expression is an unfavorable risk factor for the survival of oropharyngeal squamous cell carcinoma patients after surgery.
Jennifer Koffler,Dana Holzinger,Gustavo A Acuña Sanhueza,Gustavo A Acuña Sanhueza,Christa Flechtenmacher,Karim Zaoui,Bernd Lahrmann,Niels Grabe,Peter K. Plinkert,Jochen Hess,Jochen Hess +10 more
TL;DR: Increased SMR3A protein expression in the pathogenesis of OPSCC, which serves as an unfavorable risk factor for patient survival, is demonstrated for the first time.