J
Jochen Hess
Researcher at German Cancer Research Center
Publications - 125
Citations - 6990
Jochen Hess is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cancer. The author has an hindex of 39, co-authored 110 publications receiving 6071 citations. Previous affiliations of Jochen Hess include University of Würzburg & Heidelberg University.
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Journal ArticleDOI
Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway.
Dana Holzinger,Christa Flechtenmacher,Nataly Henfling,Ines Kaden,Niels Grabe,Niels Grabe,Bernd Lahrmann,Bernd Lahrmann,Markus Schmitt,Jochen Hess,Michael Pawlita,Franz X. Bosch +11 more
TL;DR: If only formalin‐fixed biopsy material is available, the marker combination high p16INK4a/low pRb is well suited to identify OPSCC with biologically active HPV16 which represent a distinct OPSCC entity with improved prognosis.
Journal ArticleDOI
Mitochondrial RNA modifications shape metabolic plasticity in metastasis
Sylvain Delaunay,Gloria Pascual,Bohai Feng,Kevin Klann,Mikaela Behm,Agnes Hotz-Wagenblatt,Karsten Richter,Karim Zaoui,Esther Herpel,Christian Münch,Sabine Dietmann,Jochen Hess,Salvador Aznar Benitah,Michaela Frye +13 more
TL;DR: In this article , two NOP2/Sun RNA methyltransferase 3 (NSUN3)-dependent RNA modifications, 5-methylcytosine (m 5 C) and its derivative 5-formylcytoxine (f 5 C), drive the translation of mitochondrial mRNA to power metastasis.
Journal ArticleDOI
Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma.
Pilar Bayo,Pilar Bayo,Adriana Jou,Adriana Jou,Adriana Jou,Albrecht Stenzinger,Chunxuan Shao,Madeleine Gross,Madeleine Gross,Alexandra Jensen,Niels Grabe,Christel Herold Mende,Pantelis Varvaki Rados,Juergen Debus,Wilko Weichert,Peter K. Plinkert,Peter Lichter,Kolja Freier,Jochen Hess,Jochen Hess +19 more
TL;DR: It is concluded that SOX2 inhibits tumor cell motility in HNSCC cells and that lowSOX2 expression serves as a prognosticator to identify HNS CC patients at high risk for treatment failure.
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Up-regulation of BOB.1/OBF.1 expression in normal germinal center B cells and germinal center-derived lymphomas.
Axel Greiner,Kerstin Müller,Jochen Hess,Klaus Pfeffer,H. Konrad Muller-Hermelink,Thomas Wirth +5 more
TL;DR: It is shown that expression of BOB.1/OBF.1 is regulated within the B cell lineage and represents a characteristic feature of germinal center-derived tumors that is useful in their identification.
Journal ArticleDOI
Mitochondrial RNA modifications shape metabolic plasticity in metastasis
Sylvain Delaunay,Gloria Pascual,Bohai Feng,Kevin Klann,Mikaela Behm,Agnes Hotz-Wagenblatt,Karsten Richter,Karim Zaoui,Esther Herpel,Christian Münch,Sabine Dietmann,Jochen Hess,Salvador Aznar Benitah,Michaela Frye +13 more
TL;DR: In this paper , two NOP2/Sun RNA methyltransferase 3 (NSUN3)-dependent RNA modifications, 5-methylcytosine (m 5 C) and its derivative 5-formylcytoxine (f 5 C), drive the translation of mitochondrial mRNA to power metastasis.