E
Erwin Ludo Roggen
Researcher at Novozymes
Publications - 121
Citations - 3190
Erwin Ludo Roggen is an academic researcher from Novozymes. The author has contributed to research in topics: Haemophilus ducreyi & Epitope. The author has an hindex of 32, co-authored 120 publications receiving 2905 citations. Previous affiliations of Erwin Ludo Roggen include Institute of Tropical Medicine Antwerp & Karolinska Institutet.
Papers
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Journal ArticleDOI
Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools
Jason A. Greenbaum,Pernille Andersen,Martin J Blythe,Huynh-Hoa Bui,Raul E. Cachau,James E. Crowe,Matthew N. Davies,A. S. Kolaskar,Ole Lund,Sherrie L. Morrison,Brendan Mumey,Yanay Ofran,Jean-Luc Pellequer,Clemencia Pinilla,Julia Ponomarenko,Gajendra P. S. Raghava,Marc H V Van Regenmortel,Erwin Ludo Roggen,Alessandro Sette,Avner Schlessinger,Johannes Söllner,Martin S. Zand,Bjoern Peters +22 more
TL;DR: By developing common datasets, standardized data formats, and the means with which to consolidate information, it is hoped to greatly enhance the development of B‐cell epitope prediction tools.
Journal ArticleDOI
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
David A. Basketter,Harvey J. Clewell,Ian Kimber,Annamaria Rossi,Bas J. Blaauboer,Robert Burrier,Mardas Daneshian,Chantra Eskes,Alan M. Goldberg,Nina Hasiwa,Sebastian Hoffmann,Joanna Jaworska,Thomas B. Knudsen,Robert Landsiedel,Marcel Leist,Paul A. Locke,Gavin Maxwell,James M. McKim,Emily A. McVey,Gladys Ouedraogo,Grace Patlewicz,Olavi Pelkonen,Erwin Ludo Roggen,Costanza Rovida,Irmela Ruhdel,Michael Schwarz,Andreas Schepky,Greet Schoeters,Nigel Skinner,Kerstin Trentz,Marian Turner,Philippe Vanparys,James D. Yager,Joanne Zurlo,Thomas Hartung +34 more
TL;DR: In this paper, the authors present a roadmap for how to overcome the acknowledged scientific gaps for the full replacement of systemic toxicity testing using animals, which is a major concern for the current state of the art.
Journal ArticleDOI
Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology
Sarah Gordon,Mardas Daneshian,Joke A. Bouwstra,Francesca Caloni,Samuel Constant,Donna E. Davies,Gudrun Dandekar,Carlos A. Guzmán,Eric Fabian,Eleonore Haltner,Thomas Hartung,Thomas Hartung,Nina Hasiwa,Patrick Hayden,Helena Kandarova,Sangeeta Khare,Harald F. Krug,Carsten Kneuer,Marcel Leist,Guoping Lian,Uwe Marx,Marco Metzger,Katharina Ott,Pilar Prieto,Michael S. Roberts,Erwin Ludo Roggen,Tewes Tralau,Claudia Catharina Maria Van Den Braak,Heike Walles,Claus-Michael Lehr +29 more
TL;DR: An international group of experts in the field of epithelial barriers was convened from academia, industry and regulatory bodies to present both the current state of the art of non-animal models of the skin, intestinal and pulmonary barriers and to discuss future directions for both the development of new models and the refinement of existing test methods.
Patent
Glycosylated proteins having reduced allergenicity
TL;DR: In this article, the reduction of allergenicity by N-glycosylation of proteins is discussed, and the present invention relates to the field of immunology, in particular allergicity.
Journal ArticleDOI
Seroprevalence and Incidence of Sexually Transmitted Diseases in a Rural Ugandan Population
H U Wagner,E. Van Dyck,Erwin Ludo Roggen,Andrew J. Nunn,Anatoli Kamali,Anatoli Kamali,D S Schmid,J G Dobbins,Daan W. Mulder +8 more
TL;DR: The results of this exploratory study indicate that all STDs included are common in this rural population and the high HSV-2 prevalence rate among adolescents suggests that HSV -2 may be an important risk factor for HIV-1 infection.