J
John C. S. Harding
Researcher at University of Saskatchewan
Publications - 145
Citations - 4461
John C. S. Harding is an academic researcher from University of Saskatchewan. The author has contributed to research in topics: Porcine reproductive and respiratory syndrome virus & Fetus. The author has an hindex of 30, co-authored 143 publications receiving 3907 citations. Previous affiliations of John C. S. Harding include Washington University in St. Louis & University of Veterinary Medicine Vienna.
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Journal ArticleDOI
Decreased electrogenic anionic secretory response in the porcine colon following in vivo challenge with Brachyspira spp. supports an altered mucin environment.
TL;DR: This research demonstrates for the first time that the niche mucin environment produced by two infectious spirochete spp.
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Targeting NF-κB with Nanotherapy in a Mouse Model of Adult T-Cell Leukemia/Lymphoma
TL;DR: In this article, a nano-delivery system that simultaneously inhibits both canonical (p65) and noncanonical (p100) NF-κB signaling pathways locally in tumors after systemic administration was developed.
“ Periweaning Failure to Thrive Syndrome (PFTS)” - difficulties of investigating an emerging clinical problem
TL;DR: A syndrome in newly weaned pigs exhibiting anorexia followed by a catabolic series of events leading to body store depletion is explored and speculative reasoning that might be mechanistic in development is provided.
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Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience.
Kyu-Sang Lim,Jian Cheng,Austin M. Putz,Qian Dong,Qian Dong,Xuechun Bai,Hamid Beiki,Christopher K. Tuggle,Michael K. Dyck,Pig Gen Canada,Frederic Fortin,John C. S. Harding,Graham Plastow,Jack C. M. Dekkers +13 more
TL;DR: In this paper, the authors investigate population-level gene expression profiles in the blood of 912 healthy F1 barrows at ~ 27 days of age for associations with performance and health before and after their exposure to a natural polymicrobial disease challenge.
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Experimental infectious challenge in pigs leads to elevated fecal calprotectin levels following colitis, but not enteritis.
Jéssica Aparecida Barbosa,Lucas A Rodrigues,Daniel A Columbus,Juan C. P. Aguirre,John C. S. Harding,Vinícius de Souza Cantarelli,Matheus O. Costa,Matheus O. Costa +7 more
TL;DR: In this paper, the authors investigated the usefulness of fecal calprotectin as a biomarker of intestinal inflammation in Brachyspira hyodysenteriae and Salmonella Typhimurium infected pigs.