J
John H. Cardellina
Researcher at Montana State University
Publications - 155
Citations - 7979
John H. Cardellina is an academic researcher from Montana State University. The author has contributed to research in topics: Calanolide A & Cell killing. The author has an hindex of 48, co-authored 154 publications receiving 7576 citations. Previous affiliations of John H. Cardellina include University of Illinois at Urbana–Champaign & United States Department of Commerce.
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Identification of a Bis-guanylhydrazone [4,4′-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a Novel Chemotype for Inhibition of Chk2 Kinase
Andrew G. Jobson,John H. Cardellina,Dominic A. Scudiero,Sudhir Kondapaka,Hongliang Zhang,Hijoo Kim,Robert H. Shoemaker,Yves Pommier +7 more
TL;DR: In vitro data show the specific inhibition of Chk2 kinase activity by NSC 109555, a novel chemotype for the development of potent and selective inhibitors of ChK2, which may ultimately be useful in combination with current DNA-damaging agents used in the clinic.
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Clavepictines A and B: cytotoxic quinolizidines from the tunicate Clavelina picta
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‘Biomimetic’ oxidative dimerization of korupensamine A: Completion of the first total synthesis of michellamines A, B, and C
Gerhard Bringmann,Sven Harmsen,Jörg Holenz,Torsten Geuder,Roland Götz,Paul A. Keller,Rainer Walter,Yali F. Hallock,John H. Cardellina,Michael R. Boyd +9 more
TL;DR: In this paper, the first synthetic access to michellamine A (1), a C2-symmetric antiviral naturally occurring quateraryl, is described, by oxidative ‘dimeriza
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Isoflavonoids and Coumarins from Glycyrrhiza uralensis: Antibacterial Activity against Oral Pathogens and Conversion of Isoflavans into Isoflavan-Quinones during Purification
Stefan Gafner,Chantal Bergeron,Jacquelyn R. Villinski,Markus Godejohann,Pavel Kessler,John H. Cardellina,Daneel Ferreira,Karine Feghali,Daniel Grenier +8 more
TL;DR: Phytochemical investigation of a supercritical fluid extract of Glycyrrhiza uralensis has led to the isolation of 20 known isoflavonoids and coumarins, and glycycarpan, a new pterocarpan.
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Anti-HIV Alkaloids from Toddalia asiatica
Mohammad A. Rashid,Kirk R. Gustafson,Yoel Kashman,John H. Cardellina,James B. McMahon,Michael R. Boyd +5 more
TL;DR: Bioassay-directed fractionation of a Toddalia asiatica (Rutaceae) extract concentrated anti-HIV activity into fractions rich in quaternary alkaloids identified nitidine, a benzo[c]phenanthridine alkaloid, and magnoflorine, an aporphinoid alkaloidal, have been isolated and identified.