J
John H. Cardellina
Researcher at Montana State University
Publications - 155
Citations - 7979
John H. Cardellina is an academic researcher from Montana State University. The author has contributed to research in topics: Calanolide A & Cell killing. The author has an hindex of 48, co-authored 154 publications receiving 7576 citations. Previous affiliations of John H. Cardellina include University of Illinois at Urbana–Champaign & United States Department of Commerce.
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Cellular Inhibition of Checkpoint Kinase 2 (Chk2) and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor PV1019 (7-Nitro-1H-indole-2-carboxylic acid
Andrew Jobson,George T. Lountos,Philip L. Lorenzi,Jenny Llamas,John Connelly,David Cerna,Joseph E. Tropea,Akikazu Onda,Gabriele Zoppoli,Sudhir Kondapaka,Guangtao Zhang,Natasha J. Caplen,John H. Cardellina,Stephen S. Yoo,Anne Monks,Christopher Self,David S. Waugh,Robert H. Shoemaker,Yves Pommier +18 more
TL;DR: In this article, the cocrystal structure of PV1019 bound in the ATP binding pocket of Chk2 confirmed enzymatic/biochemical observations that PV 1019 acts as a competitive inhibitor of ChK2 with re
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HIV-inhibitory natural products. 11. Comparative studies of sulfated sterols from marine invertebrates.
Tawnya C. McKee,John H. Cardellina,Raffaele Riccio,Maria Valeria D'Auria,Maria Iorizzi,Luigi Minale,Robert Moran,Robert J. Gulakowski,James B. McMahon +8 more
TL;DR: Overall, sulfated sterols active against HIV-1 were also active againstAIDS, and those compounds which were sulfated on the sterol D ring were completely inactive against both HIV- 1 and HIV-2.
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HIV inhibitory natural products. 3. Diterpenes from and
Kirk R. Gustafson,Murray H. G. Munro,John W. Blunt,John H. Cardellina,James B. McMahon,Robert J. Gulakowski,Gordon M. Cragg,Paul Alan Cox,Linda S. Brinen,Jon Clardy,Michael R. Boyd +10 more
TL;DR: Extracts of the tropical rainforest trees Homalanthus acuminatus and Chrvsobalanus icaco were active in the NCI AIDS-antiviral screen.
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HIV inhibitory natural products. 11. Structure, absolute stereochemistry, and synthesis of conocurvone, a potent, novel HIV-inhibitory naphthoquinone trimer from a Conospermum sp
Laurent A. Decosterd,Ian Parsons,Kirk R. Gustafson,John H. Cardellina,James B. McMahon,Gordon M. Cragg,Yoshiko Murata,Lewis K. Pannell,J. R. Steiner +8 more
TL;DR: In this paper, a trimeric naphthoquinone derivative, conocurvone, was used as the active anti-HIV constituent of an extract from a Conospermum sp. extract.
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Zerumbone, an HIV-Inhibitory and Cytotoxic Sesquiterpene of Zingiber Aromaticum and Z. Zerumbet
TL;DR: Zerumbone and 4-O-acetylafzelin were isolated from organic extracts of rhizomes of Zingiber aromaticum (Zingiberaceae) as discussed by the authors.