J
Jonathan C.R. Jones
Researcher at Northwestern University
Publications - 145
Citations - 12245
Jonathan C.R. Jones is an academic researcher from Northwestern University. The author has contributed to research in topics: Hemidesmosome & Integrin. The author has an hindex of 63, co-authored 145 publications receiving 11745 citations.
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Journal ArticleDOI
A simplified laminin nomenclature
Monique Aumailley,Leena Bruckner-Tuderman,William G. Carter,Rainer Deutzmann,David Edgar,Peter Ekblom,Jürgen Engel,Eva Engvall,Erhard Hohenester,Jonathan C.R. Jones,Hynda K. Kleinman,M. Peter Marinkovich,George R. Martin,Ulrike Mayer,Guerrino Meneguzzi,Jeffrey H. Miner,Kaoru Miyazaki,Manuel Patarroyo,Mats Paulsson,Vito Quaranta,Joshua R. Sanes,Takako Sasaki,Kiyotoshi Sekiguchi,Lydia Sorokin,Jan F. Talts,Jan F. Talts,Karl Tryggvason,Jouni Uitto,Ismo Virtanen,Klaus von der Mark,Ulla M. Wewer,Yoshihiko Yamada,Peter D. Yurchenco +32 more
TL;DR: A new identification system for a trimer using three Arabic numerals, based on the alpha, beta and gamma chain numbers is introduced, which is introduced for laminin trimers.
Journal Article
Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
Valerie M. Weaver,Sophie A. Lelièvre,Johnathon N. Lakins,Micah A Chrenek,Jonathan C.R. Jones,Filippo G. Giancotti,Zena Werb,Mina J. Bissell +7 more
TL;DR: In this paper, the authors investigated the molecular mechanism whereby malignant and nonmalignant mammary epithelial cells become insensitive to apoptosis and showed that regardless of growth status, the formation of polarized, three-dimensional structures driven by basement membrane confers protection against apoptosis.
Journal ArticleDOI
β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
Valerie M. Weaver,Sophie A. Lelièvre,Johnathon N. Lakins,Micah A Chrenek,Jonathan C.R. Jones,Filippo G. Giancotti,Zena Werb,Mina J. Bissell +7 more
TL;DR: Results indicate that integrin-induced polarity may drive tumor cell resistance to apoptosis-inducing agents via effects on NFkappaB.
Journal ArticleDOI
Desmosomes and hemidesmosomes: structure and function of molecular components.
TL;DR: A more active role in transmitting signals that control morphogenesis during development and possibly even regulate cell growth and differentiation are being defined for cytoplasmic and membrane components of these junctions.
Journal ArticleDOI
Processing of laminin-5 and its functional consequences : role of plasmin and tissue-type plasminogen activator
TL;DR: Evidence is provided that laminin-5 is a multifunctional protein that can act under certain circumstances as a motility and at other times as an adhesive factor.