J
Jonathan H. Freedman
Researcher at National Institutes of Health
Publications - 35
Citations - 2175
Jonathan H. Freedman is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Caenorhabditis elegans & RNA interference. The author has an hindex of 22, co-authored 35 publications receiving 1974 citations. Previous affiliations of Jonathan H. Freedman include Duke University & Research Triangle Park.
Papers
More filters
Journal ArticleDOI
Standardizing global gene expression analysis between laboratories and across platforms
Theodore Bammler,Richard P. Beyer,Sanchita Bhattacharya,Gary A. Boorman,Abee L. Boyles,Blair U. Bradford,Roger E. Bumgarner,Pierre R. Bushel,Kabir Chaturvedi,Dongseok Choi,Michael L. Cunningham,Shibing Deng,Holly K. Dressman,Rickie D. Fannin,Fredrico M. Farin,Jonathan H. Freedman,Rebecca C. Fry,Angel Harper,Michael C. Humble,Patrick Hurban,Terrance J. Kavanagh,William K. Kaufmann,Kathleen F. Kerr,Li Jing,Jodi Lapidus,Michael R. Lasarev,Jianying Li,Yi-Ju Li,Edward K. Lobenhofer,Xinfang Lu,Renae L. Malek,Sean Milton,Srinivasa R. Nagalla,Jean P. O'Malley,Valerie S. Palmer,Patrick Pattee,Richard S. Paules,Charles M. Perou,Ken Phillips,Li-Xuan Qin,Yang Qiu,Sean D. Quigley,Matthew Rodland,Ivan Rusyn,Leona D. Samson,David A. Schwartz,Yan Shi,Jung Lim Shin,Stella O. Sieber,Susan H. Slifer,Marcy C. Speer,Peter S. Spencer,Dean I. Sproles,James A. Swenberg,William A. Suk,Robert C. Sullivan,Ru Tian,Raymond W. Tennant,Signe A. Todd,Charles J. Tucker,Bennett Van Houten,Brenda K. Weis,Shirley Xuan,Helmut Zarbl +63 more
TL;DR: In this paper, the authors proposed a method for standardizing global gene expression analysis between laboratories and across platforms, which can be found in Section 5.2.1.1].
Journal ArticleDOI
Use of non-mammalian alternative models for neurotoxicological study.
Randall T. Peterson,Richard Nass,Windy A. Boyd,Jonathan H. Freedman,Ke Dong,Toshio Narahashi +5 more
TL;DR: In this review, applications of four non-mammalian species, zebrafish, cockroach, Drosophila, and Caenorhabditis elegans, in the investigation of neurotoxicology and neurological diseases are presented.
Journal ArticleDOI
Global transcriptome and deletome profiles of yeast exposed to transition metals.
Yong Hwan Jin,Paul E Dunlap,Sandra J. McBride,Hanan Al-Refai,Pierre R. Bushel,Jonathan H. Freedman +5 more
TL;DR: This study identified genes and cognate signaling pathways that respond to exposure to essential and non-essential metals and genes that are essential for survival in the presence of these metals were identified.
Journal ArticleDOI
A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay
Windy A. Boyd,Sandra J. McBride,Julie R. Rice,Daniel W. Snyder,Jonathan H. Freedman,Jonathan H. Freedman +5 more
TL;DR: A high-throughput method is described for quantifying the reproductive capacity of C. elegans exposed to chemicals for 48 h from the last larval stage (L4) to adulthood using a COPAS Biosort to verify that automated measurements were comparable to those of traditional observational studies.
Book ChapterDOI
Caenorhabditis elegans as a model in developmental toxicology
TL;DR: A C. elegans larval growth and development assay for medium- and high-throughput screening using the COPAS Biosort flow cytometer is described and descriptions of the data and subsequent analysis are provided.