R
Richard P. Beyer
Researcher at University of Washington
Publications - 105
Citations - 7151
Richard P. Beyer is an academic researcher from University of Washington. The author has contributed to research in topics: Gene expression & Gene. The author has an hindex of 42, co-authored 105 publications receiving 6401 citations. Previous affiliations of Richard P. Beyer include United States Department of the Interior & Michigan State University.
Papers
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Journal ArticleDOI
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
Patrick Weydt,Victor V. Pineda,Anne E. Torrence,Randell T. Libby,Terrence F. Satterfield,Eduardo R. Lazarowski,Merle L. Gilbert,Gregory J. Morton,Theodor K. Bammler,Andrew D. Strand,Libin Cui,Richard P. Beyer,Courtney N. Easley,Annette C. Smith,Dimitri Krainc,Serge Luquet,Ian R. Sweet,Michael W. Schwartz,Albert R. La Spada +18 more
TL;DR: Reduced expression of PGC-1alpha target genes in HD patient and mouse striatum is document, which may link transcription dysregulation and mitochondrial dysfunction in HD.
Journal ArticleDOI
Standardizing global gene expression analysis between laboratories and across platforms
Theodore Bammler,Richard P. Beyer,Sanchita Bhattacharya,Gary A. Boorman,Abee L. Boyles,Blair U. Bradford,Roger E. Bumgarner,Pierre R. Bushel,Kabir Chaturvedi,Dongseok Choi,Michael L. Cunningham,Shibing Deng,Holly K. Dressman,Rickie D. Fannin,Fredrico M. Farin,Jonathan H. Freedman,Rebecca C. Fry,Angel Harper,Michael C. Humble,Patrick Hurban,Terrance J. Kavanagh,William K. Kaufmann,Kathleen F. Kerr,Li Jing,Jodi Lapidus,Michael R. Lasarev,Jianying Li,Yi-Ju Li,Edward K. Lobenhofer,Xinfang Lu,Renae L. Malek,Sean Milton,Srinivasa R. Nagalla,Jean P. O'Malley,Valerie S. Palmer,Patrick Pattee,Richard S. Paules,Charles M. Perou,Ken Phillips,Li-Xuan Qin,Yang Qiu,Sean D. Quigley,Matthew Rodland,Ivan Rusyn,Leona D. Samson,David A. Schwartz,Yan Shi,Jung Lim Shin,Stella O. Sieber,Susan H. Slifer,Marcy C. Speer,Peter S. Spencer,Dean I. Sproles,James A. Swenberg,William A. Suk,Robert C. Sullivan,Ru Tian,Raymond W. Tennant,Signe A. Todd,Charles J. Tucker,Bennett Van Houten,Brenda K. Weis,Shirley Xuan,Helmut Zarbl +63 more
TL;DR: In this paper, the authors proposed a method for standardizing global gene expression analysis between laboratories and across platforms, which can be found in Section 5.2.1.1].
Journal ArticleDOI
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo.
Evelyn S. Vincow,Gennifer E. Merrihew,Ruth E. Thomas,Nicholas J. Shulman,Richard P. Beyer,Michael J. MacCoss,Leo J. Pallanck +6 more
TL;DR: The findings show that the PINK1–Parkin pathway promotes mitophagy in vivo and, unexpectedly, also promotes selective turnover of mitochondrial RC subunits.
Journal ArticleDOI
The External RNA Controls Consortium: a progress report.
Shawn C. Baker,Steven R. Bauer,Richard P. Beyer,James D. Brenton,Bud Bromley,John Burrill,Helen C. Causton,Michael P Conley,Rosalie K. Elespuru,Michael J. Fero,Carole Foy,James C. Fuscoe,Xiaolian Gao,David Gerhold,Patrick Gilles,Federico Goodsaid,Xu Guo,Joe Hackett,Richard D. Hockett,Pranvera Ikonomi,Rafael A. Irizarry,Ernest S. Kawasaki,Tamma Kaysser-Kranich,Kathleen F. Kerr,Gretchen L. Kiser,Walter H. Koch,Kathy Y Lee,Chunmei Liu,Z. Lewis Liu,Anne Bergstrom Lucas,Chitra Manohar,Garry Miyada,Zora Modrusan,Helen Parkes,Raj K. Puri,Laura H. Reid,Thomas B. Ryder,Marc L. Salit,Raymond R. Samaha,Uwe Scherf,Timothy J Sendera,Robert Setterquist,Leming Shi,Richard Shippy,Jesus Soriano,Elizabeth A. Wagar,Janet A. Warrington,Mickey Williams,Frederike Wilmer,Michael A Wilson,Paul K. Wolber,Xiaoning Wu,Renata Zadro +52 more
TL;DR: The External RNA Controls Consortium (ERCC) is developing commonly agreed-upon and tested controls for use in expression assays, a true industry-wide standard control.
Journal ArticleDOI
Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
Francesco Bedogni,Rebecca D. Hodge,Gina E. Elsen,Branden R. Nelson,Ray A. M. Daza,Richard P. Beyer,Theo K. Bammler,John L.R. Rubenstein,Robert F. Hevner +8 more
TL;DR: Tbr1 coordinately regulates regional and laminar identity of postmitotic cortical neurons, and exhibits ectopic axon projections to the hypothalamus and cerebral peduncle.