Jordan R. Beach

TL;DR: Two approaches are used to improve the resolution of SIM to allow live cell imaging of dynamic cellular processes, including endocytosis and cytoskeleton remodeling, and it is demonstrated that the resolution for these methods is comparable with or better than other SR approaches yet allowed us to image at far higher speeds, and for far longer durations.

TL;DR: This work argues that individual NM II isoforms are potentially performing both iso form-specific and isoform-redundant functions while coassembled with other NM IIisoforms.

TL;DR: The authors reveal the origin, organization, and functions of a major cytoskeletal network during synapse maturation and report that actomyosin arcs at the T cell synapse are formin-generated structures that directly propel T cell receptor cluster movement.

TL;DR: Non-muscle myosin IIB plays a major role in applying force on the nucleus to facilitate nuclear translocation through tight spaces during 3D invasive migration, while non-muscles in the nucleus are critical for generating force during active protrusion.

TL;DR: Transition between myosin IIC/myosin IIB expression is a critical feature of EMT that contributes to increases in invasive behavior and downstream of heterogeneous nuclear ribonucleoprotein-E1, an effector of TGF-β signaling.