Mithun Pasham

TL;DR: Two approaches are used to improve the resolution of SIM to allow live cell imaging of dynamic cellular processes, including endocytosis and cytoskeleton remodeling, and it is demonstrated that the resolution for these methods is comparable with or better than other SR approaches yet allowed us to image at far higher speeds, and for far longer durations.

TL;DR: This methodology sets a new standard for imaging membrane dynamics in single cells and multicellular assemblies with high resolution and high precision.

TL;DR: Enriched primary Sertoli cells or MSC-1 cells were transplanted as allografts into the renal subcapsular area of naive BALB/c mice, and their survival in graft sites was compared to increase understanding of testicular immune privilege.

TL;DR: Under conditions of AP2 ablation, the existence of a subclass of relatively short-lived CCPs lacking AP2 is detected, arguing that distinct classes of CCPs could provide specialized functions in regulating EGFR recycling and signaling.

TL;DR: Electron microscopy shows images of particles at various stages of engulfment into tightly fitting membrane invaginations, consistent with the interpretation that rotavirus particles drive their own uptake, and observations suggest a molecular model for membrane disruption and DLP penetration.