J
Jörg Wilting
Researcher at University of Göttingen
Publications - 151
Citations - 8664
Jörg Wilting is an academic researcher from University of Göttingen. The author has contributed to research in topics: Lymphatic system & Lymphangiogenesis. The author has an hindex of 53, co-authored 147 publications receiving 8179 citations. Previous affiliations of Jörg Wilting include Boston Children's Hospital & University of Freiburg.
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Journal ArticleDOI
VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane
Su Ja Oh,Markku M. Jeltsch,Ralf Birkenhäger,John E.G. McCarthy,Herbert A. Weich,Bodo Christ,Kari Alitalo,Jörg Wilting +7 more
TL;DR: Both the regular pattern and the typical structure of these lymphatics suggest that CAM is a suitable site to study the in vivo effects of potential lymphangiogenic factors.
Journal ArticleDOI
The role of Pax-1 in axial skeleton development
TL;DR: It is suggested that Pax-1 function is required for essential steps in ventral sclerotome differentiation, i.e. for the transition from the mesenchymal stage to the onset of chondrogenesis.
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Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth
Romulo Albuquerque,Takahiko Hayashi,Won Gil Cho,Mark E. Kleinman,Sami Dridi,Atsunobu Takeda,Judit Z. Baffi,Kiyoshi Yamada,Hiroki Kaneko,Martha G. Green,Joseph Chappell,Jörg Wilting,Herbert A. Weich,Satoru Yamagami,Shiro Amano,Nobuhisa Mizuki,Jonathan Steven Alexander,Martha L. Peterson,Rolf A. Brekken,Masanori Hirashima,Seema Capoor,Tomohiko Usui,Balamurali K. Ambati,Balamurali K. Ambati,Jayakrishna Ambati +24 more
TL;DR: The existence of a splice variant of the gene encoding vascular endothelial growth factor receptor-2 that encodes a secreted form of the protein, designated soluble VegFr-2 (sVegfr-2), that inhibits developmental and reparative lymphangiogenesis by blocking Vegf-c function is reported.
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Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
TL;DR: It is shown that Pax1 protein expression in thymic epithelial cells can be detected throughoutThymic development and in the adult, and expression levels of major thymocyte surface markers remains unchanged.
Journal ArticleDOI
The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues
Jörg Wilting,Maria Papoutsi,Bodo Christ,Kypros H. Nicolaides,Constantin von Kaisenberg,J. Borges,G. Björn Stark,Kari Alitalo,Stanislav I. Tomarev,Charlotte M. Niemeyer,Jochen Rössler +10 more
TL;DR: It is shown that Prox1 is a reliable marker for LECs in normal and pathologic human tissues, coexpressed with VEGFR‐3 and CD31, which are less reliable markers for L ECs and BECs, respectively, because exceptions from their normal expression patterns are found in pathologic tissues.