José Luiz Fernandes Vieira

TL;DR: It is demonstrated that BCP significantly ameliorates both the clinical and pathological parameters of EAE and strongly supports the effectiveness of BCP as a novel molecule to target in the development of effective therapeutic agents for MS.

TL;DR: Radical cure with primaquine was highly effective in preventing early recurrence and may also improve blood schizontocidal efficacy against chloroquine-resistant P vivax malaria.

TL;DR: In vivo CQ resistance in patients with uncomplicated P. vivax malaria, with use of CQ and primaquine simultaneously, in the Brazilian Amazon is estimated and previous exposure to malaria and a higher initial mean parasitemia were associated with resistance but not with age or gender.

TL;DR: Two regions of Para state differ in the clinical manifestations and severity of confirmed envenomation by T. obscurus which suggests a toxicity variation resulting from the diversity of T. occurus venom in different areas of the Brazilian Amazon basin, and that T. serrulatus antivenom can be successfully used against T. obstruction.

TL;DR: Primaquine has the potential to reduce malaria-related anaemia at day 42 and beyond by preventing recurrent parasitaemia and will require accurate diagnosis of G6PD deficiency to reduce the risk of drug-induced haemolysis in vulnerable individuals.