C
Cindy S. Chu
Researcher at Mahidol University
Publications - 75
Citations - 2528
Cindy S. Chu is an academic researcher from Mahidol University. The author has contributed to research in topics: Plasmodium vivax & Primaquine. The author has an hindex of 24, co-authored 68 publications receiving 1905 citations. Previous affiliations of Cindy S. Chu include Monash University & Churchill Hospital.
Papers
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Journal ArticleDOI
Malaria Burden and Artemisinin Resistance in the Mobile and Migrant Population on the Thai–Myanmar Border, 1999–2011: An Observational Study
Verena I. Carrara,Khin Maung Lwin,Aung Pyae Phyo,Elizabeth A. Ashley,Jacher Wiladphaingern,Kanlaya Sriprawat,Marcus J. Rijken,Machteld E. Boel,Rose McGready,Stephane Proux,Cindy S. Chu,Pratap Singhasivanon,Nicholas J. White,François Nosten +13 more
TL;DR: Francois Nosten and colleagues evaluate malaria prevalence and incidence in the mobile population on the Myanmar side of the border with Thailand between 1999 and 2011 and also assess resistance to artemisinin.
Journal ArticleDOI
Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes
Benoit Malleret,Benoit Malleret,Ang Li,Rou Zhang,Kevin S. W. Tan,Rossarin Suwanarusk,Carla Claser,Jee Sun Cho,Esther G. L. Koh,Cindy S. Chu,Cindy S. Chu,Sasithon Pukrittayakamee,Mah Lee Ng,Florent Ginhoux,Lai Guan Ng,Chwee Teck Lim,François Nosten,François Nosten,Georges Snounou,Georges Snounou,Laurent Rénia,Bruce Russell +21 more
TL;DR: 2 hitherto unsuspected features of P vivax invasion, a narrow preference for immature reticulocytes and a rapid remodeling of the host cell, provide important insights pertinent to the pathobiology of the P v Vivax infection.
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Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria
Alejandro Llanos-Cuentas,Marcus V. G. Lacerda,Tran Tinh Hien,Iván D. Vélez,Chayadol S Namaik-Larp,Cindy S. Chu,Maria F Villegas,Fernando Val,Wuelton Marcelo Monteiro,Marcelo A M Brito,Monica R. F. Costa,Raul Chuquiyauri,Martin Casapia,Chau H Nguyen,Sandra Aruachan,Ratchadaporn Papwijitsil,François Nosten,Germana Bancone,Brian Angus,Stephan Duparc,Graham Craig,Victoria M Rousell,Siôn W. Jones,Elizabeth Hardaker,Donna D Clover,Lindsay Kendall,Khadeeja Mohamed,Gavin C. K. W. Koh,Viviana M Wilches,John J Breton,Justin A. Green +30 more
TL;DR: Among patients with normal G6PD enzyme activity, the decline in hemoglobin level with tafenoquine did not differ significantly from that with primaquine, and tafinoquine showed efficacy for the radical cure of P. vivax malaria, although tafanoquine was not shown to be noninferior to Primaquine.
Journal ArticleDOI
A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax
Bruce Russell,Rossarin Suwanarusk,Céline Borlon,Fabio T. M. Costa,Cindy S. Chu,Marcus J. Rijken,Kanlaya Sriprawat,Lucile Warter,Esther G. L. Koh,Benoit Malleret,Yves Colin,Yves Colin,Olivier Bertrand,Olivier Bertrand,John H. Adams,Umberto D'Alessandro,Georges Snounou,François Nosten,Laurent Rénia +18 more
TL;DR: A protocol for an ex vivo P vivax invasion assay that can be easily deployed in laboratories located in endemic countries is described, based on mixing enriched cord blood reticulocytes with matured, trypsin-treated P v Vivax schizonts concentrated from clinical isolates.
Journal ArticleDOI
Malaria in children
TL;DR: Present knowledge and controversies in relation to the epidemiology, pathophysiology, diagnosis, treatment, and prevention of malaria in children, aimed at clinicians who manage children with malaria, especially in resource-poor settings are discussed.