J
Joseph J. Eron
Researcher at University of North Carolina at Chapel Hill
Publications - 569
Citations - 49427
Joseph J. Eron is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 99, co-authored 511 publications receiving 44857 citations. Previous affiliations of Joseph J. Eron include Duke University.
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Journal ArticleDOI
Timing of HAART initiation and clinical outcomes in human immunodeficiency virus type 1 seroconverters
Michele Jonsson Funk,Jennifer S Fusco,Stephen R. Cole,James C. Thomas,Kholoud Porter,Jay S. Kaufman,Marie Davidian,Alice White,Katherine E Hartmann,Joseph J. Eron +9 more
TL;DR: Compared with deferring in a given month, HAART initiation at CD4 cell counts less than 500/ μL (but not 500-799/μL) was associated with slower disease progression, and the absolute and relative effects of treatment with robust 95% confidence intervals (CIs) were estimated.
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Antiretroviral Drug Resistance in HIV-1–Infected Patients Experiencing Persistent Low-Level Viremia During First-Line Therapy
Babafemi Taiwo,Sébastien Gallien,Evgenia Aga,Heather J. Ribaudo,Richard Haubrich,Daniel R. Kuritzkes,Joseph J. Eron +6 more
TL;DR: Population sequencing was performed for persons identified with persistent low-level viremia in 2 clinical trials, and detection of new mutations was associated with higher HIV-1 RNA levels during persistentLow-level Viremia.
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Resistance to HIV Integrase Strand Transfer Inhibitors among Clinical Specimens in the United States, 2009-2012
TL;DR: Almost 1 in 6 US patients undergoing integrase GRT for clinical decision making harbors significant resistance, with Q148 and N155 pathways equally common.
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High Levels of Human Immunodeficiency Virus Type 1 in Blood and Semen of Seropositive Men in Sub-Saharan Africa
John R. Dyer,Peter N. Kazembe,Pietro Vernazza,Bruce L. Gilliam,Martin Maida,Dick Zimba,Irving F. Hoffman,Rachel A. Royce,Jody Schock,Susan A. Fiscus,Myron S. Cohen,Joseph J. Eron +11 more
TL;DR: High levels of human immunodeficiency virus type 1 (HIV-1) replication, as reflected in HIV-1 RNA concentrations in blood and semen, probably contribute to both rapid disease progression and enhanced sexual transmission in sub-Saharan Africa.
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Generalizing Evidence from Randomized Trials using Inverse Probability of Sampling Weights
Ashley L. Buchanan,Michael G. Hudgens,Stephen R. Cole,Katie R. Mollan,Paul E. Sax,Eric S. Daar,Adaora A. Adimora,Joseph J. Eron,Michael J. Mugavero +8 more
TL;DR: An inverse probability of sampling weighted (IPSW) estimator is considered for generalizing trial results to a target population and is shown to be consistent and asymptotically normal.